著者
大宮 望 山本 久志 大場 允晶 丸山 友希夫 中邨 良樹
出版者
公益社団法人 日本経営工学会
雑誌
日本経営工学会論文誌 (ISSN:13422618)
巻号頁・発行日
vol.67, no.2, pp.92-99, 2016 (Released:2016-09-07)
参考文献数
13

近年,情報システムは企業にとって経営上,なくてはならない存在となってきている.情報システムの保守工程は,開発工程より費用が多く掛るといわれており,経営課題の一つとなっている.その原因の一つに,バグに関係する問い合わせがある.この問い合わせは,発生することを予測することが出来ないため,準備が出来ずに対応に多くの時間を要する.バグに関係する問い合わせが発生する要因については,様々な研究がなされているが,明確な分析はなされていない.そこで本研究では,バグに関係する問い合わせの内容,時間及び件数をクラスタ分析し,考察することによって,その発生要因を明らかにする.これをもとにバグに関する問い合わせの発生を,予測するモデルを提案する.これに加えて,予測モデルを実現場で利用するために「情報提供シート」も合わせて提案する.
著者
杉浦 靖夫 木原 正光 杉田 昭夫
出版者
公益社団法人 日本水産学会
雑誌
日本水産学会誌 (ISSN:00215392)
巻号頁・発行日
vol.26, no.6, pp.565-569, 1960 (Released:2008-02-29)
参考文献数
6

We set forth already on the ecology of Pinnotheres sinensis found in Tapes japonica. As similar observations were made on the same item of Pinnotheres gordoni found in the same clam, the result is given in the present paper. Pinnotheres gordoni is tolerant for host. It was found in such many bivalves at Kisarazu as Tapes japonica, Mytilus edulis, Ostrea (Crassostrea) gigas, Meretrix lusoria, Mactra veneriformis, Chlamys nipponensis and Umbonium (Suchium) moniliferum(gastropod). The rate of clams with the crab shows some extent of seasonal variation as being it is very low during the season from August to November, in which the water temperature runs from 16°C to 29°C, but is considerably high during the period from December to July in which the water temperature ranging between 10°C and 26°C (Table 1, Fig. 1). It seems to be that Pinnotheres gordoni is somewhat related ecologically to Pinnotheres sinensis, because of these crabs are apt to live in the same host (Table 2). The host, Tapes japonica, suffers a certain amount of harm by the crab in guestion. The rate (W×l00/SW; W=total weight of flesh of the clam; SW=shell weight of it) is 49.8±12.1% in normal clam, but 41.6±12.6% in symbionts.
著者
山内 豊
出版者
日本混相流学会
雑誌
混相流 (ISSN:09142843)
巻号頁・発行日
vol.27, no.1, pp.11-17, 2013-03-15 (Released:2013-06-05)
参考文献数
11

Developments of natural resources in the Arctic region are becoming active in the recent years. Commercial use of the northern sea route is taking on realness with a decrease of sea ice area along the Arctic coast. Also Arctic and Antarctic observation is important to clarify a global climatic change. Icebreakers are indispensable to the support for the development, the escort for cargo ships and the polar observation in ice-covered waters. The technology on icebreaker's performance is improving steadily, responding to those missions. This paper shows the typical characteristics of icebreaker and introduces several technologies to improve the performance.
著者
Susan Nancarrow Joanne Bradbury Sabrina Winona Pit Steven Ariss
出版者
(公社)日本産業衛生学会
雑誌
Journal of Occupational Health (ISSN:13419145)
巻号頁・発行日
vol.56, no.4, pp.292-300, 2014 (Released:2014-10-03)
参考文献数
22
被引用文献数
40

Objectives: “Intention to leave” (ITL) has been used interchangeably with the more positive construct “intention to stay” (ITS). The implicit assumption appears to be that both constructs represent different sides of the same coin. This study challenges this assumption. The objectives were (i) to test whether these constructs were similar measures of the same construct, and (ii) to assess the strength of the relationships between ITL and ITS with work-related outcomes. Methods: The Workforce Dynamics Questionnaire (WDQ) was administered to 298 staff. The WDQ included two items on ITL and was supplemented with three items on ITS. Structural equation modelling (SEM) was used. Results: The response rate was 43%. The correlation between the two constructs was negative and quite high (r=−0.84), indicating potential issues with discriminant validity. However, the constructs behaved differently in relation to job satisfaction and job integration. ITS was a strong predictor (0.95, p<0.001), whereas ITL was not significantly related (0.34, p=0.195) to JS. The direct effects of JI on ITS was 0.30 and on ITL was −0.42. The indirect effects of JI were more contrasting, being 0.56 for ITS and −0.30 for ITL, via job satisfaction. Conclusions: This is the first study amongst British health and social care workers that has demonstrated that ITS and ITL are not measuring the same construct. While there is overlap, care should be taken when using these constructs interchangeably, particularly when measuring these concepts in organizations and when developing retention programs, policies, or activities to modify ITS and ITL.(J Occup Health 2014; 56: 292-300)
著者
余田 敬子 尾上 泰彦 西田 超 金子 富美恵 須納瀬 弘
出版者
日本口腔・咽頭科学会
雑誌
口腔・咽頭科 (ISSN:09175105)
巻号頁・発行日
vol.24, no.2, pp.171-177, 2011 (Released:2011-09-14)
参考文献数
12
被引用文献数
1

性感染症クリニックで, 淋菌・クラミジア検査を行った女性169人の職業と, 男性81人の性交渉の相手について検討した. 女性の92%を占めたソープランド (ソープ) 従業女性では, 淋菌の咽頭陽性者が性器より多く, クラミジアは性器陽性者が咽頭より多かった. ソープ以外の性風俗店従業女性においても, 淋菌・クラミジアの咽頭と性器の陽性者が存在した. 性風俗従業でない女性にも, 淋菌・クラミジアの陽性者があった.男性では, 咽頭の淋菌陽性者の89%, 性器の淋菌陽性者の93%, 咽頭のクラミジア陽性者全員, 性器のクラミジア陽性者の77%が, 性風俗従業女性からの感染と推察された. また, 少数ではあるが, 特定の女性から淋菌・クラミジアに感染した人と思われた人が存在した.
著者
Satoshi Akiba Hidenori Yamaguchi Satomi Kumazawa Mayuko Oka Takashi Sato
出版者
一般社団法人 日本動脈硬化学会
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
vol.14, no.5, pp.219-225, 2007 (Released:2007-11-06)
参考文献数
40
被引用文献数
5 8

Aim: An extract of Ginkgo Biloba L. was shown to have preventive effects on cardiovascular disorders, but the molecular mechanisms of its actions remain to be elucidated. Since matrix metalloproteinases (MMPs) are implicated in the rupture of atherosclerotic plaques and the subsequent occurrence of acute coronary syndrome, we examined the effects of a leaf extract (Ginkgolon-24) on the production of MMP-1 in human coronary smooth muscle cells stimulated with oxidized low-density lipoprotein (oxLDL) and 4-hydroxynonenal, which are factors proposed to play a pivotal role in atherogenesis.Methods: The production of MMP-1 and phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 were estimated by immunoblotting. The tyrosine-phosphorylated form of platelet-derived growth factor receptor β (PDGFR-β) was analyzed by immunoprecipitation of the receptor followed by immunoblotting.Results: oxLDL and 4-hydroxynonenal accelerated the production of MMP-1 with the preceding phosphorylation of ERK1/2 and PDGFR-beta;. Pretreatment with Ginkgolon-24 inhibited the production of MMP-1 and phosphorylation of ERK1/2 induced by oxLDL and 4-hydroxynonenal, but did not affect the production and phosphorylation induced by phorbol ester. Furthermore, Ginkgolon-24 prevented tyrosine phosphorylation of the receptor induced by oxLDL and 4-hydroxynonenal.Conclusion: These results suggest that Ginkgo Biloba extract suppresses the oxLDL- and 4-hydroxynonenal-induced production of MMP-1, probably through the inhibition of PDGFR-β activation in human coronary smooth muscle cells.
著者
山西 良典 杉原 健一郎 井上 林太郎 松下 光範
出版者
日本感性工学会
雑誌
日本感性工学会論文誌 (ISSN:18840833)
巻号頁・発行日
vol.14, no.1, pp.155-162, 2015 (Released:2015-02-20)
参考文献数
16
被引用文献数
2

Comic has, recently, been known as one of the most beloved entertainment and affective medium in the world. This paper describes about extraction of Kansei highlight from comic using social data. There seems to be Kansei highlight that most people approve in comic, because several related books where impressive scenes and captions for a comic are gathered are published. Through the experiments on impressions, we obtained social data for comics. We used the social data to extract Kansei highlight from comic. Through the three types of experiments, we confirmed that social data was available for extracting Kansei highlight from comic. Moreover, we designed the interface of social reading system for comic considering interaction on existing social service. We believe that the extraction of Kansei highlight from comic using social data increases attraction of digital comic.
著者
Kenta Yonezuka Jun Shimodaira Michiro Tabata Shoko Ohji Akira Hosoyama Daisuke Kasai Atsushi Yamazoe Nobuyuki Fujita Takayuki Ezaki Masao Fukuda
出版者
公益財団法人 応用微生物学・分子細胞生物学研究奨励会
雑誌
The Journal of General and Applied Microbiology (ISSN:00221260)
巻号頁・発行日
pp.2016.06.003, (Released:2016-12-17)
参考文献数
78
被引用文献数
22

Pseudomonas putida is well-known for degradation activities for a variety of compounds and its infections have been reported. Thus, P. putida includes both clinical and nonclinical isolates. To date, no reports have examined the phylogenetic relationship between clinical and nonclinical isolates of the P. putida group. In this study, fifty-nine strains of P. putida group containing twenty-six clinical, and thirty-three nonclinical, isolates, were subjected to phylogenetic and taxonomic analyses based on 16S rRNA gene sequences and nine housekeeping gene sequences, including argS, dnaN, dnaQ, era, gltA, gyrB, ppnK, rpoB, and rpoD, to obtain insights into the diversity of species in this group. More than 97.6% similarity was observed among the 16S rRNA gene sequences of all the strains examined, indicating that the resolution of 16S rRNA gene sequences is inadequate. Phylogenetic analysis based on the individual housekeeping genes listed above improved the resolution of the phylogenetic trees, which are different from each other. Multilocus sequence analysis (MLSA) based on the concatenated sequences of the nine genes significantly improved the resolution of the phylogenetic tree, and yielded approximately the same results as average nucleotide identity (ANI) analysis, suggesting its high reliability. ANI analysis classified the fifty-nine strains into twenty-six species containing seventeen singletons and nine strain clusters based on the 95% threshold. It also indicated the mixed distribution of clinical and nonclinical isolates in the six clusters, suggesting that the genomic difference between clinical and nonclinical isolates of the P. putida group is subtle. The P. putida type strain NBRC 14164T is a singleton that is independently located from the P. putida strains distributed among the six clusters, suggesting that the classification of these strains and the differentiation of species in the P. putida group should be re-examined. This study greatly expands insights into the phylogenetic diversity of the P. putida group.
著者
Shotaro Ide Noriho Sakamoto Shintaro Hara Atsuko Hara Tomoyuki Kakugawa Yoichi Nakamura Yoji Futsuki Koichi Izumikawa Yuji Ishimatsu Katsunori Yanagihara Hiroshi Mukae
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.56, no.1, pp.79-83, 2017-01-01 (Released:2017-01-01)
参考文献数
20
被引用文献数
4

Although pneumothorax has been reported to be a major pulmonary adverse event in patients treated with pazopanib, a multikinase inhibitor, drug-induced interstitial lung disease (DILD) has not been reported. A 74-year-old Japanese man who received pazopanib for the treatment of femoral leiomyosarcoma and lung metastasis presented with dyspnea and fatigue. He had mild interstitial pneumonia when pazopanib treatment was initiated. Chest computed tomography revealed progressive bilateral ground-glass opacity (GGO) and traction bronchiectasis. We diagnosed DILD due to pazopanib. The patient's pazopanib treatment was interrupted and a steroid was administered. The symptoms and GGO were improved with treatment. Physicians should be aware of DILD due to pazopanib in patients with pre-existing interstitial lung disease.
著者
加藤 隆寛 田中 聡 渡邉 暁洋 織田 順 浅香 えみ子 有賀 徹 畝井 浩子 鏑木 盛雄 菊池 憲和 桑原 健 篠原 高雄 峯村 純子 眞野 成康 西澤 健司 定光 大海
出版者
一般社団法人 日本臨床救急医学会
雑誌
日本臨床救急医学会雑誌 (ISSN:13450581)
巻号頁・発行日
vol.19, no.6, pp.725-734, 2016-12-31 (Released:2016-12-31)
参考文献数
18

目的:救急医療における薬剤師のおかれた状況や不足するスキルは不明であり,これらを把握することを目的にアンケートを実施した。方法:日本臨床救急医学会の薬剤師会員を対象に,救急医療・集中治療への従事,現在および今後実施したい業務,実施希望のトレーニングコースについて調査した。結果:195名より回答を得た。救急医療への従事は23.1%,集中治療が68.2%であった。救急医療での業務は主に薬品管理で(77.8%),患者対応はおもに依頼された時のみ(64.4%)行われていた。トレーニングコースは中毒,循環器系が求められていた。集中治療では抗菌薬,循環器系薬の介入が多かったが,フィジカルアセスメントの実施率は低かった。結論:救急医療に従事する薬剤師は少ない。全患者へ対応できる体制の整備,中毒,循環器系に関するトレーニングが有効と考えられた。集中治療ではフィジカルアセスメントの活用が次の課題になると考えられた。
著者
土生 芳樹
出版者
近畿作物・育種研究会
雑誌
作物研究 (ISSN:1882885X)
巻号頁・発行日
vol.61, pp.85-90, 2016 (Released:2016-12-26)
参考文献数
27

近年の交配育種においてはマーカー育種法やゲノミックセレクション法などの進展により多数の交配後代個体から目的のゲノム組成を持つ個体を選抜する効率が飛躍的に向上したが,減数分裂期組み換えの位置や変異誘発の頻度を積極的に制御する試みはほとんど行われていない.減数分裂期組み換えはゲノム中で限られた領域(ホットスポット)に集中しているため,ホットスポット以外の領域に組み換えを誘導する技術の確立は効率的な作物育種にむけた重要な課題の一つである.組み換えが起きないゲノム領域はDNAの局所的な「固さ」と関係していることが知られており,この固さを決める要因がエピゲノムと呼ばれるDNA-ヒストンタンパク質複合体の化学修飾である.本稿では作物への有用形質付与を目的としたゲノムの構造・機能の改変を効率的に行う手段として,従来の方法とは異なるエピゲノム制御の観点からのアプローチを紹介する.
著者
高橋 雅雄 磯貝 和秀 古山 隆 宮 彰男 蛯名 純一
出版者
特定非営利活動法人バードリサーチ
雑誌
Bird Research (ISSN:18801587)
巻号頁・発行日
vol.12, pp.A65-A71, 2016 (Released:2016-12-31)
参考文献数
26

2014-2015年冬期と2015-2016年冬期に,関東地方の都市部と農村部の計32か所の湿性草原でオオセッカの生息調査を行ない,13か所で計94個体を確認した.そのうち4か所は都市部に位置し,住宅地等で囲まれて孤立した環境だった.また3か所では耕作放棄田で,別の3か所では自然生態観察公園で生息が確認され,これらの環境も越冬地として利用されることが確かめられた。さらに,オオセッカは多様なタイプのヨシ原環境で確認され,従来考えられていた以上に多様な植生環境を利用する可能性が示唆された.
著者
Eun-Ji Go Sang-Heon Lee
出版者
理学療法科学学会
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.28, no.12, pp.3350-3353, 2016 (Released:2016-12-27)
参考文献数
25
被引用文献数
7

[Purpose] The aim of this study was to investigate the effect of an intensive sensorimotor stimulation program on the motor function of chronic hemiparetic patients. [Subjects and Methods] The subjects were three chronic stroke patients whose sensory function was intact, who had Mini-Mental State Examination − Korean version scores of more than 26, and manual muscle test scores of more than fair for affected shoulder and elbow. The research design was an A-B single subject experimental design. The intervention consisted of 4 baselines phase sessions, and 12 sensorimotor stimulation phase sessions. The sensory and motor stimulation was performed for 30 minutes per session. The efficacy of the program was evaluated by the Box and Block test, and the 10-second test. [Results] Box and Block test and 10-second test scores of each subject improved after the 8 weeks intervention. [Conclusion] The intensive sensorimotor stimulation program for the upper extremity may be an efficacious method for improving the function of the affected limb of chronic stroke patients.
著者
Yoshimune Nonomura Azusa Yamaguchi
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.45, no.2, pp.206-208, 2016-02-05 (Released:2016-02-05)
参考文献数
9
被引用文献数
1

The friction behaviors of water and aqueous solutions of thickener were evaluated between a contact probe with a striped rough surface and a substrate. When the probe surface is flat, the contact states are the boundary lubrication and fluid film lubrication states for water and the thickener aqueous solutions, respectively. In contrast, for the contact probe with a striped rough surface, friction occurred under fluid lubrication state for both water and thickener solutions. These results indicate that the liquid in the depression on the striped rough surfaces changes the regime of friction.