著者
Takamitsu YAMAMOTO Yoichi KATAYAMA Toshiki OBUCHI Kazutaka KOBAYASHI Hideki OSHIMA Chikashi FUKAYA
出版者
社団法人 日本脳神経外科学会
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
vol.52, no.7, pp.475-481, 2012 (Released:2012-07-25)
参考文献数
32
被引用文献数
3 32

Minimally conscious state (MCS) is characterized by inconsistent but clearly discernible behavioral evidence of consciousness, and can be distinguished from coma and the vegetative state (VS). Ten MCS patients were evaluated neurologically and electrophysiologically over 3 months after the onset of brain injury, and were treated by spinal cord stimulation (SCS). A flexible four-contact, cylinder electrode was inserted into the epidural space of the cervical vertebrae, and placed at the C2-C4 levels. Stimulation was applied for 5 minutes every 30 minutes during the daytime at an intensity that produced motor twitches of the upper extremities. We used 5 Hz for SCS, considering that the induced muscle twitches can be a useful functional neurorehabilitation for MCS patients. Eight of the 10 MCS patients satisfied the electrophysiological inclusion criteria, which we proposed on the basis of the results of deep brain stimulation for the treatment of patients in the VS. Seven patients recovered from MCS following SCS therapy, and were able to carry out functional interactive communication and/or demonstrate the functional use of two different objects. Cervical SCS increased cerebral blood flow (CBF) diffusely in the brain, and CBF increased by 22.2% during the stimulation period compared with CBF before stimulation in MCS patients (p < 0.0001, paired t-test). Five-Hz cervical SCS could increase CBF and induce muscle twitches of the upper extremities. This SCS therapy method may be suitable for treating MCS.
著者
佐多 祐策 酒井 朗 唐木 保照 土持 綱治
出版者
昭和大学学士会
雑誌
昭和医学会雑誌 (ISSN:00374342)
巻号頁・発行日
vol.12, no.1, pp.31-36,53, 1952-03-01 (Released:2010-09-09)
参考文献数
13

Congenital anal atresia is a malformation which is fairly frequently encountered in the clinic. Recently, the authors happened to fall upon a case of simple anal atresia and a case of complicated vesical anal atresia accompanied by female spurious hermaphrodism in the Department. Therefore, the cases are reported and discussed in the present paper for the purpose of comparative considerations.Most cases of simple anal atresia or complicated anal atresia are usually first diagnosed on the occash, n when the clinical symptoms of ileus have appeared. Plastic operation for the case of simple anal atresia, and artificial anus for the case of complicated vesical anal atresia was indicated. Surgical treatment of plastic operation of anus was performed on these cases 4 months after the first operations.In the case of vesical anal atresia, the fact that it was accompanied by female spurious hermaphrodism was discovered during the second operation. Therefore, a review on the embryological pathology of complicated anal atresia was attempted, and discussions were made on the genesis of hermaphrodism with reference to the past literatures on the subject.

1 0 0 0 OA 広島のかき

著者
山崎 妙子
出版者
一般社団法人 日本調理科学会
雑誌
調理科学 (ISSN:09105360)
巻号頁・発行日
vol.24, no.3, pp.270-275, 1991-08-20 (Released:2013-04-26)
参考文献数
7
著者
和田 英太郎
出版者
公益社団法人 日本アイソトープ協会
雑誌
RADIOISOTOPES (ISSN:00338303)
巻号頁・発行日
vol.35, no.3, pp.136-146, 1986-03-15 (Released:2010-07-21)
参考文献数
47
被引用文献数
10 8
著者
山本 達
出版者
公益社団法人 日本表面科学会
雑誌
表面科学 (ISSN:03885321)
巻号頁・発行日
vol.35, no.10, pp.580-581, 2014-10-10 (Released:2014-10-21)
被引用文献数
1
著者
指田 吾郎 岩間 厚志
出版者
一般社団法人 日本血液学会
雑誌
臨床血液 (ISSN:04851439)
巻号頁・発行日
vol.56, no.2, pp.111-118, 2015 (Released:2015-03-12)
参考文献数
38

近年の研究成果は,造血器腫瘍をジェネティック変異とエピジェネティック変異が複数蓄積した病態として理解する重要性を示している。骨髄異形成症候群(MDS)はクローナルな造血幹細胞による悪性腫瘍であり,造血不全状態を呈して,一部が急性骨髄性白血病(MDS/AML)へと移行する。近年の詳細なゲノムワイドの遺伝子解析によって,TET2, DNMT3A, EZH2, ASXL1などのエピジェネティック制御遺伝子の変異がMDSで次々と同定された。これまでに蓄積されたがんにおけるエピゲノム異常の知見とあわせて,エピジェネティック制御異常を伴うMDS発症の分子基盤が徐々に解明されつつある。
著者
沢田 史子 大藪 多可志 吉田 武稔 竹中 幸三郎 B.C. Wolverton
出版者
一般社団法人 電気学会
雑誌
電気学会論文誌E(センサ・マイクロマシン部門誌) (ISSN:13418939)
巻号頁・発行日
vol.122, no.6, pp.300-305, 2002 (Released:2003-03-28)
参考文献数
10
被引用文献数
1 4

Plants have the capability to purify various atmospheric chemicals. There are, however, few studies on the plant purification-characteristics. In this paper, the purification capability of pothos plant for formaldehyde was investigated. Formaldehyde is one of the typical chemical substances, which cause a sick-building syndrome. The purification capability (Pa) was introduced using a tin oxide gas sensor-output. The experiment was conducted for six different soils. It is recognized that the purification capabilities considerably differ according to the kinds of soils. Namely, the soils, which are mixed with the porous materials such as ceramics, tend to have the high capability. It became obvious that room temperature had also the effects on the purification capability. The optimum temperature, at which the plant had the high capability, was about 22°C.
著者
森重 浩光 真柴 賛 千頭 憲一郎 山本 哲司
出版者
中国・四国整形外科学会
雑誌
中国・四国整形外科学会雑誌 (ISSN:09152695)
巻号頁・発行日
vol.23, no.2, pp.341-345, 2011 (Released:2014-03-31)
参考文献数
9

Abstract We report two cases of osteochondritis dissecans (OCD) in identical twin male badminton players. The younger brother presented at the age of 15 years complaining of a two-year history of right knee pain during sports activity. Physical examination showed a positive result in the patella grinding test, but no range of motion limitation. Plain radiography showed that the lateral femoral groove had irregularity and a radiolucent region, and a diagnosis of OCD was made on the basis of magnetic resonance imaging (MRI). Arthroscopy demonstrated softening of the OCD lesion and partial cracking of the cartilage. The OCD lesion was fixed using bone strips. Five months after surgery, MRI demonstrated almost total disappearance of the lesion, and the patient returned to his original sports activity. The elder brother presented at the age of 16 years with a three-month history of left knee pain during sports. Physical examination revealed only mild tenderness of the patellofemoral joint. Plain radiography and MRI showed OCD in the lateral femoral groove, and arthroscopy demonstrated the lesion but no cracking of the cartilage. As had been the case for the younger brother, surgery was performed using bone strips. Because the lesion appeared to show good remodeling into normal bone on MRI at three months after surgery, the patient returned to his original level of sport. Although familial incidence of OCD is not unusual, cases in identical twins are very rare. The similarities of both site and onset timing of these OCD lesions suggest that some genetic factor may contribute to the cause of OCD other than overloading due to repetitive and strong sports activity. Also, our clinical results indicate that fixation with bone strips is a useful therapeutic option for OCD in the femoral groove to facilitate a prompt return to sports activity.
著者
常盤 洋子 國清 恭子
出版者
北関東医学会
雑誌
北関東医学 (ISSN:13432826)
巻号頁・発行日
vol.56, no.4, pp.295-302, 2006 (Released:2006-12-26)
参考文献数
54

【目 的】 文献研究により, 出産体験の自己評価に関する研究の現状と課題を明らかにし, 出産体験の自己評価に関する研究に有効な変数を得ることを目的とする. 【研究方法】 1960年~2001年までの論文を対象に, "childbirth experience", "self evaluation", "scale" をキーワードにして, CINAHL, MedLine, 医学中央雑誌を中心に検索した. 【結 果】 131論文が検出され, 出産体験の自己評価について記述がなされ, 学術論文の形式が整っている47論文を選んで概観した. 出産体験の臨床的意義が明らかにされ, 出産体験の自己評価のアセスメントに有効な産科的, 心理・社会的変数が抽出された. 【結 論】 今後の研究の課題と方向性について, 以下, 3つの視点を明らかにした. (1)分娩経過の正常・異常による出産体験のとらえ方の相違を比較できる大きいサンプルによる調査の必要性, (2)出産体験の自己評価と産後の心理的健康 (例えば, 産後うつ傾向, 自尊感情) との関連についての実証的研究の必要性, (3)出産体験の再構築と意味づけに関する実践的研究の必要性が示唆された.
著者
岸本 正実 幣 憲一郎 田中 真理子 和田 啓子 福田 美由紀 姫野 雅子 桑原 晶子 小川 蓉子 木戸 詔子 稲垣 暢也 田中 清
出版者
公益社団法人 日本栄養・食糧学会
雑誌
日本栄養・食糧学会誌 (ISSN:02873516)
巻号頁・発行日
vol.62, no.5, pp.253-258, 2009 (Released:2009-10-29)
参考文献数
13
被引用文献数
4

肥満は通常body mass index (BMI) によって判定されるが, 本来肥満は脂肪細胞過多である。そこで本研究では生活習慣病患者166名を対象に, BMIとbioimpedance analysis (BIA) 法による体組成の関係を検討した。BMIは体脂肪量と, 相関係数0.914と強く相関したが, 除脂肪量とは相関係数0.434と中等度にとどまり, BMIと除脂肪量の相関係数は, BMI≧25 kg/m2群ではBMI<25 kg/m2群より低かった。BMIによる肥満 (≧25 kg/m2) と, 体脂肪率による肥満 (男性≧20%, 女性≧30%) の関係は, 後者の判定に対して前者の特異度は高いが, 感度は低く, BMI25 kg/m2以上では, ほぼ確実に体脂肪率による肥満が存在するが, 25 kg/m2未満でもその存在を否定できない。栄養アセスメントにおいて, BMIに加えて体組成評価の併用が必要であり, また感度・特異度などによる解析を考慮すべきである。
著者
橋口 公一
出版者
公益財団法人 日本学術協力財団
雑誌
学術の動向 (ISSN:13423363)
巻号頁・発行日
vol.18, no.2, pp.2_78-2_81, 2013-02-01 (Released:2013-06-04)
被引用文献数
1 1
著者
荻原 彰
出版者
一般社団法人 日本環境教育学会
雑誌
環境教育 (ISSN:09172866)
巻号頁・発行日
vol.19, no.1, pp.1_129-138, 2009 (Released:2011-01-25)
参考文献数
29

In this research, I surveyed the United States' educational reform and its effect on environmental education and also the response of environmental education to reform. I tried to obtain suggestions for Japan. The score of achievement tests is valued highly in the No Child Left Behind Act. Therefore, environmental education is disregarded.   Environmental education deals with this crisis by two means: first, making of standards, and second, insitence that environmental education is useful as a tool of educational reform.   Through several research projects, it has been clarified that environmental education is useful for improving scholastic attainments and reducing discipline problems. This is because environmental education gives meaning to the study of subjects and develops a sense of belonging and self-efficacy for students. Schools that succeed in the improvement of scholastic attainments and the reduction of discipline problems through environmental education have common features. Such a feature is, for instance, development of an interdisciplinary curriculum by an interdisciplinary team.   Finally, proposals are given for improvement of environmental education in Japan.
著者
荒井 克弘
出版者
日本教育社会学会
雑誌
教育社会学研究 (ISSN:03873145)
巻号頁・発行日
vol.72, pp.37-52, 2003-05-25 (Released:2011-08-04)
参考文献数
23
被引用文献数
1 1

This paper discusses the features of the Japanese and US educational assessment systems, analyzing the systems of university entrance exams and national educational surveys.1. Educational Assessment as a Linkage of High Schools and Universities.As a result of the expansion of higher education, both Japan and the U. S. have faced the same articulation issue: the need for systems that are suitable for the phase of mass education.In the United States, for example, a guidance-type admission test (ACT) was introduced four decades ago to complement the conventional selection-type admission test (SAT). The new test has contributed to the efficiency of selection and placement processes, but has not enhanced students' motivation. Improving their academic abilities in their preparations for colleges still remains as an important issue.Japan, on the other hand, has introduced the policy of “the diversification of an entrance examination” as a specific remedy in recent years, in order to cool off exam hell, a major complication of the “diploma society.” However, this new trial was not successful, in that it not only expanded the mismatch between admissions requirements and university education, but has also had ramifications for the high school curricula.2. National Survey of Educational Achievement as a Tool for Educational SupportNational educational surveys basically provide us with materials for considering the current reality of educational achievements and future prospects. With technological progress, however, we can combine various kinds of achievement test data in different settings, through the data scale of the national educational survey. This makes it possible to measure and compare achievement scores among different areas within one country, as well as among two or more countries.Furthermore, this plan may contribute to the development of new articulation systems between high schools and universities in the U.S. in the near future. The proposal to restart a national education survey was also recently proposed in Japan, but the purpose is restricted to data collection concerning educational achievement and school assessment.The result shows that Japan and the U. S. have different traditions of the educational assessment research and different social environments. In particular, there is a clear difference in the independence of evaluation organizations and in the autonomy of an evaluation system. It also tells us of the importance of separating schools and administration/evaluation agencies, in order to maintain the objectivity and freedom of choices of evaluation systems. For this reason, the U.S. has been able to continue to hold educational assessments.
著者
中村 慶春 恩田 昌彦 内田 英二 井上 松応 山村 進 松谷 毅 丸山 弘 横山 滋彦 石川 紀行 田尻 孝 山下 精彦 山口 敏和 憚 暁青
出版者
一般社団法人 日本消化器内視鏡学会
雑誌
日本消化器内視鏡学会雑誌 (ISSN:03871207)
巻号頁・発行日
vol.38, no.12, pp.2848-2852_1, 1996-12-20 (Released:2011-05-09)
参考文献数
15

膵癌を疑われた33例に対して, 十二指腸乳頭括約筋を弛緩させるためにニトログリセリン舌下錠を投与し経口的膵管内視鏡検査を施行した. 最大2錠 (0.6mg) の投与により外径2.2mmの膵管鏡は容易に乳頭を通過しえた (29/33, 87.9%) . 通過不能の4例はすべて膵頭部癌症例で, カニュレーションを深く行えず十分にガイドワイヤーを留置できなかったことが原因であった. 乳頭通過後に膵管内を尾部あるいは病変まで観察できたものが29例中23例であった. 血圧の変動はニトログリセリン非投与群と比し有意差を認めず, 合併症は1例も経験しなかった. ニトログリセリン投与は簡便かつ安全で, 確実に乳頭を開大させることが可能で, 経口的膵管鏡検査において有効な方法と思われた.
著者
鈴木 素之 長谷川 秀人 六信 久美子 山本 哲朗
出版者
公益社団法人 土木学会
雑誌
土木学会論文集G (ISSN:18806082)
巻号頁・発行日
vol.62, no.4, pp.445-451, 2006 (Released:2006-12-20)
参考文献数
13
被引用文献数
1 1

管理されずに自然放置された竹林の拡大による周辺環境や生態系への影響が顕在化している.森林の再生ならびに保全を検討する上で,地盤環境工学の見地から規模を拡大する竹林の諸性質を把握することは重要である.本文では,山口県下の竹林の分布状況をもとに,隣接した竹林の拡大による自然結合や他の植生または植物群落への竹の侵入の事例を報告するとともに,県内2地域を対象とした航空写真解析および現地調査により竹林の拡大速度を算出した.その結果,竹林の最前線は年間当り全体的に0.7m,局所的には2.5mで拡大していることを明らかにした.