Chemical elucidation of acute encephalopathy by ingestion of angel-wing mushroom (Pleurocybella porrigens) — involvement of three constituents in onset — Proceedings of the Japan Academy, Series B https://t.co/4BOyCSI8eR 2023 にこの分野の第一人者、静大、河岸先生の総説が。OA。
Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement https://t.co/Lbvp7epfmO 東京医科歯科大 玉村先生のラボより https://t.co/9BCQfYcFQ1
TNF-α Mediated the Disruption of Hepatic Tight Junction Expression in Blood–Biliary Barrier of Colitis via Downregulating PI3K/AKT Signaling Pathway
https://t.co/ZLOcUoF0p8
Xian-sen Jiang, Bi-le Fu, Xin-xin Yang, and Hong-yan Qin
The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine
https://t.co/dJANMGOfML
Hongye Han, Takeshi Akiyoshi, Tokio Morita, Toshiaki Tsuchitani, Momoko Nabeta, Kodai Yajima, Ayuko Imaoka, and Hisakazu Ohtani
Review 【自分用備忘録】
Innovative System or Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines
Hideyoshi Harashima
https://t.co/QYP5yr311c
BioPharmBull / 2023 Volume 46 Issue 12 Pages 1648-1660
Efficient Endocytosis of the Human Lactoferrin N-Lobe Enhances Its Antiproliferative Activity against Human Cancer Cells
https://t.co/34GumlFksk
Lactoferrin N-Lobeにはどうやら面白い活性があるらしい、面白い。
Design, Synthesis and Structure–Activity Relationship Studies of Protein Kinase CK2 Inhibitors Containing a Purine Scaffold https://t.co/jTQtyh4Gl6 https://t.co/8wgwKUNtUs
Computer Science Technology in Natural Products Research: A Review of Its Applications and Implications https://t.co/G9c0LEDSRo 初学者向きにコンサイスにまとまった総説【後で読む】自分用備忘録
生成型AIや大規模言語モデルが発達したら、天然物化学へのDS活用も更に変わるのだろうか?
Dear new researchers for Abeta(1-42) by solution and SS NMR!
Stable-isotope labelling to Abeta sample is essential for NMR study. I provided a comprehensive list for successful examples of bacterial Abeta expression systems here, https://t.co/GXENArabhF #NMR
Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ https://t.co/axZuNJbN8j 【後で読む】【自分用備忘録】Abeta凝集体に結合する化合物を単離してきている模様 https://t.co/46zjFX2gvt
Computational Screening of Inhibitory Compounds for SARS-Cov-2 3CL Protease with a Database Consisting of Approved and Investigational Chemicals https://t.co/sBJnrq5DFi
Autodock VINA利用 千葉大星野先生ら
Comparison of Immunochemical Reactions of Infliximab Innovator and Biosimilars on an Infliximab Detection Kit Used for Therapeutic Drug Monitoring https://t.co/ik9eA0WWe8 抗体医薬のバイオシミラーとオリジナル開発元の製品のスペック比較。世はバイオシミラー激戦時代に【自分用備忘録】 https://t.co/iuGn3icsch
Use of Iontophoresis Technology for Transdermal Delivery of a Minimal mRNA Vaccine as a Potential Melanoma Therapeutic https://t.co/WMEjEt9JGe 徳島大薬・小暮先生、名大・阿部先生 イオントフォレシスによるmRNAワクチンの生体へのデリバリー https://t.co/bb1c90clu4
Anorexia Assessed by Simplified Nutritional Appetite Questionnaire and Association with Medication in Older Patients Undergoing Hemodialysis https://t.co/jqEdzG3Sst https://t.co/8Ruvfzrtgm
Identification of a Functionally Efficient and Thermally Stable Outward Sodium-Pumping Rhodopsin (Be-NaR) from a Thermophilic Bacterium https://t.co/DARryJDmbf 須藤先生のところから。 https://t.co/aJMfkkPleF
Masking the Taste of Fixed-Dose Combination Drugs: Particular NSAIDs Can Efficiently Mask the Bitterness of Famotidine https://t.co/HeN4ksjvyw https://t.co/wVkdeKvFIK
Molecular mechanisms of amyloid-β peptide fibril and oligomer formation: NMR-based challenges https://t.co/wIwIjUPACA #nmr #idp
3,Feb,2023 Biophysics and Physicobiology
Some of small molecules with anti-amyloid activity may be classified into "equilibruium shifter". https://t.co/FZaEFJ2T8N
Advanced Solid-State NMR Analysis of Two Crystal Forms of Ranitidine Hydrochloride: Detection of 1H-14N Intra-/Intermolecular Correlations https://t.co/GK5ngpOko6 #nmr #ssnmr https://t.co/oixhGI4x9S
1H-NMR-Based Metabolomics for the Classification of the Roots of Paeonia lactiflora, a Constituent of Kampo Medicines #nmr #nmrchat https://t.co/n2ljxbB2oN https://t.co/hbHDZpFTSg
Development of Naturally Inspired Peptide and Protein Chemistry https://t.co/PYguq69QCm 【自分用備忘録】Complihensive review of intein mediated and intein-inspired peptide chemistry and its application https://t.co/u6cSXTKyDf
SNAP23-Mediated Perturbation of Cholesterol-Enriched Membrane Microdomain Promotes Extracellular Vesicle Production in Src-Activated Cancer Cells 小根山先生のところからSrc依存exosome分泌の系 https://t.co/kPC0k1k6Yq https://t.co/dBK0d3h4iQ
Purification of Emu IgY for Therapeutic and Diagnostic Use Based on Monoclonal Secondary Antibodies Specific to Emu IgY https://t.co/BebfPfLAEF 【自分用備忘録】エミュー!エミュー!エミューの抗体の応用 https://t.co/Y5yncXSmk9
The Many Roles of Lysophospholipid Mediators and Japanese Contributions to This Field https://t.co/8R2acW6Lhl 【自分用備忘録】青木淳賢先生総説 必読 LPAシグナリング https://t.co/IiQCRXYCB2
Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment 【siRNA-DDS-総説】 https://t.co/TKRPB7jQ5X 【自分用備忘録】 https://t.co/GFQJ8pJMRL
Multistep growth of amyloid intermediates and its inhibition toward exploring therapeutic way: A case study using insulin B chain and fibrinogen https://t.co/eAZN4fwyqK 【自分用備忘録】あっこの総説面白くない?おもしろくない?(アミロイド好き・線維好き) https://t.co/bLE3iPb3uB
An Update Mini-Review on the Progress of Azanucleoside Analogues https://t.co/nbgR1owoDZ 糖部に窒素を含むヌクレオシドアナログに関する最近の総説、抗ウイルス活性とか。核酸医薬盛り上がってます。 https://t.co/JA4PjZPdmf
Application of the Functionality Transfer Oligodeoxynucleotide for the Site-Selective Modification of RNA with a Divers Molecule https://t.co/fsqLe5k5w7 発想がちょっと面白いかも。残基特異的に特定のCを修飾とか架橋とか https://t.co/HdXls1aJPL
Multiple Stimuli-Responsive Supramolecular Gel Formed from Modified Adenosine https://t.co/a35R7YPEyW
なんかこの論文めちゃおもしろそう
アデノシン誘導体で超分子ゲル? 明治薬科大山中先生 https://t.co/MjfJxhLpsp
寺井健太先生・松田道行先生との共同研究論文がCell Struct Funct誌に掲載されました!
@kenta_terai @Phogemon
A dual promoter system to monitor IFN-γ signaling in vivo at single-cell resolution
https://t.co/p6mzFO8scM
秋山研M1松野さんの卒業研究の成果をまとめた論文がBPPB誌よりpublishされました!
Multidomain protein structure prediction using information about residues interacting on multimeric protein interfaces
https://t.co/nbcuVB92kw