著者
Yasushi Saito Yuichiro Goto Aaron Dane Kristina Strutt Ali Raza
出版者
Japan Atherosclerosis Society
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
vol.10, no.6, pp.329-336, 2003 (Released:2004-03-03)
参考文献数
18
被引用文献数
48 48

Rosuvastatin is a novel statin that has been shown to produce large dose-dependent reductions in low-density lipoprotein cholesterol (LDL-C) in Western hypercholesterolemic patients. Rosuvastatin dose response was assessed in a randomized, double-blind phase II trial in which 112 Japanese patients with fasting LDL-C > 160 and < 220 mg/dl and triglycerides < 300 mg/dl received placebo or rosuvastatin 1, 2.5, 5, 10, 20, or 40 mg once daily for 6 weeks. LDL-C change from baseline showed a linear dose response (p < 0.0001 for slope of regression line) over the rosuvastatin dose range, with each doubling of dose producing an additional 5.12% reduction. Mean reductions (least-squares mean percentage change from baseline from ANOVA) in LDL-C were 35.8% to 66.0% and significantly different from placebo at all doses (p < 0.0001). Linear dose response was also observed for total cholesterol (TC) and apolipoprotein (apo) B, but not for triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), or apo A-I or A-II. Mean changes at 6 weeks were − 25.5 to − 45.1% for TC, − 16.0 to − 26.2% for TG, + 7.5 to + 12.8% for HDL-C, − 31.9 to − 57.8% for apo B, + 5.5 to + 10.0% for apo A-I, and + 0.4 to + 8.1% for apo A-II. Rosuvastatin was well tolerated. Although there was some suggestion of increased frequency of treatment-related adverse events at higher doses, there were no clear dose relationships in safety parameters. Only one patient withdrew from the study because of a treatment-related adverse event. No patients had clinically significant elevations in liver transaminases or creatine kinase. Rosuvastatin produces good dose-related reductions in LDL-C and beneficial changes in other lipid fractions in Japanese hypercholesterolemic patients and is well tolerated.
著者
福川 康之 小田 亮 宇佐美 尋子 川人 潤子
出版者
公益社団法人 日本心理学会
雑誌
心理学研究 (ISSN:00215236)
巻号頁・発行日
pp.85.13206, (Released:2014-06-01)
参考文献数
46
被引用文献数
9 31

This study developed a Japanese version of the Perceived Vulnerability to Disease (PVD) scale. Analysis of the data from Japanese university students (N = 435) replicated the two–factor structure of the original scale: one factor that assessed beliefs about one’s own susceptibility to infectious diseases (perceived infectability) and the other factor that assessed emotional discomfort in contexts that connoted an especially high potential for pathogen transmission (germ aversion). Tests of reliability and validity for each subscale indicated overall promising results. It would appear that the results reflect at least in part an evolutionary adaptive psychological mechanism for the ancestral environment.
著者
伊藤 洋介 河辺 伸二 大羽 慧
出版者
日本建築学会
雑誌
日本建築学会構造系論文集 (ISSN:13404202)
巻号頁・発行日
vol.82, no.739, pp.1321-1327, 2017 (Released:2017-09-30)
参考文献数
12
被引用文献数
1 2

It is expected that elderly people can't remove snow on their own, and have a trouble going out. There are some ways to remove snow which do not require physical effort, but each conventional way has problems. Therefore, the authors have attempted to invent the “heating mortar block system” to remove snow. In this system, electromagnetic waves are generated by the oscillator, and then irradiated mortar blocks with. A heating mortar block is composed of 3 layers; 1. electromagnetic absorption material 2. base material (without electromagnetic absorption ability) 3. electromagnetic shielding material. Electromagnetic absorption material placed near the surface absorbs electromagnetic waves and converts it into heat. This system uses this heat to melt snow on the blocks. Electromagnetic absorption material is mortar mixed with electric arc furnace oxidizing slag as aggregate (hereinafter, called “the slag mortar”), and base material is a mortar mixed with sand as aggregate (hereinafter, called “the sand mortar”). According to preceding research, there is a correlation between abilities of electromagnetic absorption and heating. But, the characteristics of electromagnetic absorption and heating about electromagnetic absorption material composed of the slag mortar and the sand mortar has not been studied enough. So, the purpose of this study is to clarify these things and develop the base theory to design heating mortar blocks absorbing the electromagnetic waves and heating well. Ability of electromagnetic absorption is evaluated with return loss calculated by S-parameter method. Within the measuring range, following things were clarified. (1) When the sand mortar is superposed under the slag mortar, the thickness of which the sand mortar causes the prominent absorption of electromagnetic waves at specific frequency (hereinafter, called “peak”), has a period. And, it is possible to choose a thickness from some thickness by considering this period. (2) When the sand mortar is superposed under the slag mortar, it is possible to determine the thickness, by specifying the thinnest thickness through the experiment and using the equation produced in this study. (3) It is possible to adjust the temperature rises of the heating mortar block without changing the thickness of the slag mortar which is the electromagnetic absorption material, by just changing the thickness of the sand mortar. (4) When the thickness of sand mortar superposed under the slag mortar is 30mm, 62mm or 93mm and it is irradiated with electromagnetic waves of frequency 2.45GHz, the temperature rises 20.6 °C, 17.3 °C or 19.2 °C each. In these thickness, return loss also rise as a peak. (5) When the sand mortar is superposed under the slag mortar, it is possible to evaluate the heating ability by return loss.
著者
飯野 友里恵 森谷 友昭 高橋 時市郎
出版者
一般社団法人 映像情報メディア学会
雑誌
映像情報メディア学会技術報告 35.14 (ISSN:13426893)
巻号頁・発行日
pp.49-52, 2011-03-04 (Released:2017-09-21)
参考文献数
2

モーションキャプチャシステムを用いて取得されたデータを利用して,ストリートダンスの動作解析を行った.ダンス経験者と初心者のモーションデータを取得し,その違いが数値的に表れているか,特徴抽出を試みた.解析結果によれば,上級者との違いを初心者へ伝達し,練習効率を高めるための処理とシステム化を検討したので,報告する.
著者
中村 善行 藏之内 利和 高田 明子 片山 健二
出版者
公益社団法人 日本食品科学工学会
雑誌
日本食品科学工学会誌 (ISSN:1341027X)
巻号頁・発行日
vol.61, no.12, pp.577-585, 2014-12-15 (Released:2015-01-31)
参考文献数
24
被引用文献数
7 13

調理後の甘さが大きく異なる多様なサツマイモ品種·系統や育種素材を供試して,塊根のβ-アミラーゼ活性およびデンプンの含量,糊化温度と蒸しいものマルトース含有率との関係を調べた.マルトース含有率はβ-アミラーゼ活性の上昇に伴って増加したが,活性が約0.2 m mole maltose/min/mg proteinを越えると含有率の増加は抑制された.マルトース含有率とデンプン含有率との間には相関が認められなかったが,デンプン糊化温度との間には弱い負の相関が認められた.特に,β-アミラーゼ活性が高い塊根では糊化温度が低いほどマルトース含有率が高い傾向が見られた.また,デンプンの糊化温度が比較的高い品種「ベニアズマ」を本州より気温の低い北海道で栽培すると,糊化温度が有意に低下し,β-アミラーゼ活性は同等かあるいはそれ以下にも拘わらず,マルトース含有率が有意に高くなった.サツマイモの加熱調理に伴うマルトース生成には塊根のβ-アミラーゼ活性に加えてデンプンの糊化し易さも重要であると考えられた.
著者
稲木 龍元
出版者
日本デジタル教科書学会
雑誌
デジタル教科書研究 (ISSN:21887748)
巻号頁・発行日
vol.4, pp.1-16, 2017-10-27 (Released:2017-10-27)
参考文献数
6

本稿は,A特別支援学校(知的障害)におけるICT活用の事例について,重度知的障害児を対象としたこと,学校における機器整備のプロセスを含めたこと,校務への活用を含めたことを特徴とした報告である.児童生徒に対する指導では,タブレットの導入プロセスから授業活用までの様子を報告した.校務では,アンケートでの活用や校内研究による業務効率化の様子を報告した.最後に,本実践に残された課題と他の特別支援学校に事例を一般化する際の留意点を議論した.
著者
小林 武夫 石毛 美代子
出版者
日本音声言語医学会
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.53, no.2, pp.158-161, 2012 (Released:2012-06-11)
参考文献数
9
被引用文献数
1

17歳のとき月経痛がひどく,男性化作用のあるダイホルモンデポ®を投与され,音声障害を引き起こした女性を30年間にわたり追跡した.声は翻転し,話声位は低下した.18歳の初診時の話声位はB3で,30歳までこの状態が続き,48歳の現在話声位はF3となっている.この状態を声も相同と考えられる一卵性双生児の妹と比較した.ホルモン投与の当初,話声位は3半音低下を見た.自家で行った音声訓練にかかわらず,声は回復しなかった.
著者
大平 英樹
出版者
日本感情心理学会
雑誌
エモーション・スタディーズ (ISSN:21897425)
巻号頁・発行日
vol.5, no.1, pp.4-15, 2020-03-31 (Released:2020-11-11)
参考文献数
61

Psychological constructivism of affect argues that experienced emotions are constructed through two processes: 1) formation of the core affect on the basis of interoception which is neural representation of bodily signals, 2) categorization of the core affect by using concepts and contextual information. In this article, it is proposed that cultural and historical situations can affect experiences of emotions via revision of concepts and processes of co-construction of affect between individuals. For this purpose, a hierarchical Bayesian computational model of affect is introduced, and the processes of co-construction of affect are examined through computational simulation. Furthermore, importance of culture and history is discussed in the perspective of co-construction of affect.
著者
JungWon KIM Chulho OAK TaeWon JANG MaanHong JUNG BongKwon CHUN Eun-Kee PARK Ken TAKAHASHI
出版者
National Institute of Occupational Safety and Health
雑誌
Industrial Health (ISSN:00198366)
巻号頁・発行日
vol.51, no.2, pp.228-231, 2013 (Released:2013-08-31)
参考文献数
10
被引用文献数
2 3

Industrial talc has been widely circulated in the world for a long time. The pure talc has little effects on humans, but inhalation of talc contaminated with asbestos can causes severe asbestos-related diseases such as lung cancer and malignant mesothelioma. Herein, we represent a case of lung cancer after occupational exposure to industrial talc in the rubber manufacturing industry.
著者
吉川 利治
出版者
京都大学東南アジア地域研究研究所
雑誌
東南アジア研究 (ISSN:05638682)
巻号頁・発行日
vol.19, no.4, pp.363-387, 1982 (Released:2018-06-02)

Field Marshal Phibunsongkhram, the Prime Minister of Thailand during the Pacific War, is said to have been a dictator, a chauvinist and a militarist, and to have erred in trying to revive old Siam by military means. But the minutes of the Cabinet conference, Phibun's speeches, the Ratthaniyom principles, Thai Code of Valour and Phibun's own behavior during his regime reveal his thoughts and actions as a campaign to foster the civilization of Thailand and to restore her honor and face among nations.  He renamed the country "Thailand" on June 24, 1939 because the old name Siam was associated with absolute monarchy, Westerner worship, arbitary Chinese action, a national inferiority complex and old customs. It was his aim to dispel these associations and to prompt constitutional monarchy, the civilization of the country and the modernization of the people.  The Phibun regime intended to reduce Western political power and Chinese economic power. Japan also had an interest in destroying Western power in Southeast Asia and replacing it with her own. Phibun used Japanese power to carry out his policy. Japan treated Thailand as an important nation in Southeast Asia before the Pacific War, so she could move her forces through Thai territory and obtain necessary facilities. Phibun cooperated with Japan for only one year during the war, then switched to the promotion of an anti-Japanese strategic plan, because he thought that cooperation with Japan did not bring honor and face either to Thailand or to himself.
著者
小椋 たみ子 浜辺 直子
出版者
言語科学会
雑誌
Studies in Language Sciences (ISSN:24359955)
巻号頁・発行日
vol.19, no.2, pp.1-18, 2021-12-23 (Released:2021-12-21)
参考文献数
40

本研究では前言語期から文法出現期の9ヶ月から24ヶ月児の母子の遊び場面の観察録画データから、第一に、母親の事物をあらわす育児語と動作をあらわす育児語の特徴を音韻面と形態統語情報から明らかにし、子どもの年齢による育児語使用に違いがあるか否か検討した。育児語の特徴は、事物育児語、動作育児語とも特殊モーラを含む語や自立モーラの反復が大部分であった。形態統語情報については、事物育児語は格助詞を伴うあるいは格助詞の省略された育児語が単独の事物育児語より多く発せられていた。動作育児語は「する」の動詞や動作誘発助詞を伴っていた。事物育児語、動作育児語とも子ども年齢で有意差はなかった。第二に、養育者は成人語と育児語で子どもに働きかけていることから、事物語と動作語の育児語率(育児語/(育児語+成人語))がその後(33ヶ月)の子どもの幼児語、成人語の事物語、動作語獲得へ及ぼす効果と効果をおよぼす月齢について検討した。その結果、14ヶ月児の母の事物育児語率タイプ、トークンは、33ヶ月事物成人語獲得に正の効果を、また、14ヶ月児の母親の動作育児語率トークンが33ヶ月動作幼児語に正の効果を及ぼしていた。一方、24ヶ月児の母親の動作育児語率は33ヶ月の動作幼児語、動作成人語に負の効果を及ぼしていた。母親の育児語の言語入力の効果は事物語、動作語で異なり、また、子どもの年齢においても異なっていた。
著者
MURAKAMI Masataka
出版者
Meteorological Society of Japan
雑誌
気象集誌. 第2輯 (ISSN:00261165)
巻号頁・発行日
pp.2019-009, (Released:2018-11-05)
被引用文献数
5

A large amount of snowfall caused by snow clouds over the Sea of Japan sometimes severely affects social and economic activities in Japan. Therefore, snow clouds, which form and develop mainly over the ocean and bring heavy snowfall to populated coastal plains, have long been intensively studied from the perspective of disaster prediction and prevention. Most studies have analyzed data acquired by aerological, meteorological satellite, and radar observations, or have conducted numerical simulations. Because of the difficulties involved in accessing cloud systems over the ocean, however, few in situ observation data have been available, and up until the middle 1990s, many problems remained unsolved or their analysis and simulation results remained unvalidated. Here, knowledge gained from instrumented aircraft observations made from the middle 1990s through the early 2000s is reviewed, in particular with regard to the development of a convectively mixed boundary layer and the inner structures of longitudinal-mode cloud bands, Japan-Sea polar-air mass convergence zone cloud bands, and a polar low. Unsolved problems relating to the inner structures and precipitation mechanisms of snow clouds and the expected contributions of aircraft observations to further progress in these areas of atmospheric science are also briefly discussed.