著者

西村 富啓 河野 晴一 倉島 篤行 久保 博昭 小池 勇一

出版者

The Japanese Society of Clinical Pharmacology and Therapeutics

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.37, no.6, pp.353-357, 2006-11-30 (Released:2010-06-28)

参考文献数

23

被引用文献数

1 1

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Rifampicin (RFP) is one of the first-line drugs in the treatment of tuberculosis. Worldwide, the recommended administration of RFP is before breakfast, however it is commonly administered after the meal in Japan. It is known that the absorption of RFP is affected by a meal. Therefore, the effects of meal on the pharmacokinetics of rifampicin were studied in patients with tuberculosis.Ten male patients participated in this study. Five of the ten patients were given three capsules (450mg of RFP) 30 minutes before breakfast. The other five patients were given the same dose of RFP 30 minutes after breakfast. The mean age and weight were 54.6±3.3 years and 53.9±2.7kg in the group before meal and in the after the meal group, 49.8±8.4 years and 53.8±5.0kg, respectively. All the data were expressed as mean±S.D. Blood samples were taken at 0, 2, 4 and 6 hours after capsule administration. RFP concentra tions in serum were analyzed by reversed-phase high performance liquid chromatography and the relevant pharmacokinetic parameters were calculated. Group means were compared by use of nonparametric statis tics.In the group before meal, the peak concentration (Cmax) was significantly higher than that in the group after meal (9.32±0.88μg/mL versus 5.76 ± 1.04 μg/mL, p<0.05) and the AUC was also significantly higher than that in the group after meal (35.83±3.29μg/hr/mL versus 18.63±4.35μg/hr/mL, p<0.05). These results suggest that RFP should be taken 30 minutes before the meal.

著者

何星雨 倉持清美 馬場幸子

出版者

東京学芸大学学術情報委員会

雑誌

東京学芸大学紀要. 総合教育科学系 (ISSN:18804306)

巻号頁・発行日

vol.70, no.2, pp.53-60, 2019-02-28

著者

倉沢 康大 安部 亮佑 西沢 文吾

出版者

公益財団法人 山階鳥類研究所

雑誌

山階鳥類学雑誌 (ISSN:13485032)

巻号頁・発行日

vol.52, no.2, pp.133-137, 2020-12-15 (Released:2020-12-16)

参考文献数

12

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On September 16, 2009 and July 7, 2018 we observed six Wilson's Storm-petrels Oceanites oceanicus on six occasions in the Northwest Pacific off Hokkaido. These are first records for Hokkaido and the northernmost records in Japan.

著者

沼倉 茜 吉川 沙耶花 上條 篤 松田 帆 新藤 晋 池園 哲郎 加瀬 康弘 神山 信也 伊藤 彰紀 大澤 威一郎

出版者

一般社団法人 日本耳鼻咽喉科頭頸部外科学会

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.121, no.2, pp.134-138, 2018-02-20 (Released:2018-03-07)

参考文献数

15

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拍動性耳鳴に対しては, 器質的疾患の存在を疑う必要がある. 今回われわれは, 拍動性耳鳴を主訴に来院し, 横- S 状静脈洞部硬膜動静脈瘻と診断された1例を経験した. 拍動性耳鳴の診断には頸部血管の圧迫による変化と聴診が重要である. 硬膜動静脈瘻のスクリーニングには脳 MRA が優れている. しかし, 脳疾患の MRA 診断においては脳主幹動脈領域のみを関心領域とした MIP 画像が用いられることが多く, 外頸動脈系や静脈洞が関与する硬膜動静脈瘻は見落とされる可能性がある. したがって, 見落としを避けるには, MIP 画像のみならず MRA の元画像を確認することが重要である. 硬膜動静脈瘻は根治が期待できるため見落とさないことが重要である.

著者

細井 裕司 西村 忠己 下倉 良太

出版者

一般社団法人 日本聴覚医学会

雑誌

AUDIOLOGY JAPAN (ISSN:03038106)

巻号頁・発行日

vol.63, no.4, pp.217-225, 2020-08-30 (Released:2020-09-09)

参考文献数

18

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要旨: 2004年に細井は「耳軟骨に音声情報を含む振動を与えると, 気導や骨導と同程度に音声情報が明瞭に内耳に伝えられること」を発見し, この第3の音伝達経路を「軟骨伝導 (Cartilage conduction) 」と命名した。また, この現象から導き出される応用製品 (電話機, 補聴器など) について記載した。2017年には世界初の軟骨伝導補聴器が発売され, 骨導補聴器に対する優越性から骨導補聴器に代わって国内外に普及が始まっている。

著者

倉田春一 著

出版者

大鵬書房

巻号頁・発行日

1935

著者

倉田潔 著

出版者

春江堂

巻号頁・発行日

1922

著者

熊倉 啓之

出版者

静岡大学教育学部

雑誌

静岡大学教育学部研究報告. 教科教育学篇 (ISSN:0286732X)

巻号頁・発行日

vol.38, pp.35-50, 2007-03

著者

竹下 直彦 鬼倉 徳雄

出版者

一般社団法人 日本魚類学会

雑誌

魚類学雑誌 (ISSN:00215090)

巻号頁・発行日

vol.58, no.2, pp.202-205, 2011 (Released:2014-03-07)

参考文献数

26

著者

土倉 英志

出版者

日本認知科学会

雑誌

認知科学 (ISSN:13417924)

巻号頁・発行日

vol.23, no.3, pp.285-296, 2016-09-01 (Released:2017-03-01)

参考文献数

19

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In this paper, I studied college students’learning. They worked on “science cafe”projects, and successfully executed those projects. Science cafe is a type of workshop. I analyzed the following three research questions about their learning. First, did they learn about the theme termed “offstage interests”? Second, what features characterize “offstage interests”? Third, how did they learn about “offstage interests”?  To elucidate these research questions, I collected data through interviews of college students, after science cafe activities for one year had been completed. The interviews were combined with the interviewees’reflections on these activities.  By analyzing the data, I clarified the following three points. First, the college students learned about the theme termed “offstage interests.”Their learning about “offstage interests”implies that they have become interested in others’offstage activities, such as concerts. The offstage activities are out-of-sight from the onstage activities that they appreciate or in which they participate. Second, their learning about “offstage interests”comprises taking a keen interest in, and empathizing with, others’offstage activities. Third, fostering learning about “offstage interests”requires two aspects: 1) undertaking various roles in the science cafes’activities, and 2) creating a framework of activities from scratch. Finally, I considered relationships among learning about “offstage interests,”knotworking, and active learning.

著者

倉田 稔

出版者

小樽商科大学

雑誌

商学討究 : The Economic Review (Otaru University of Commerce) (ISSN:04748638)

巻号頁・発行日

vol.45, no.4, pp.1-35, 1995-03

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論説

著者

宮地 正人 仁藤 敦史 井上 章一 倉本 一宏

出版者

国際日本文化研究センター

雑誌

日本研究 (ISSN:09150900)

巻号頁・発行日

vol.55, pp.171-207, 2017-05

著者

小倉 健太郎

出版者

成城大学

雑誌

成城美学美術史 (ISSN:13405861)

巻号頁・発行日

no.21, pp.37-59, 2015-03

著者

小倉 健太郎

出版者

成城大学

雑誌

成城美学美術史 (ISSN:13405861)

巻号頁・発行日

no.19, pp.63-81, 2013-03

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American philosopher Charles Sanders Peirce (1839-1914) categorized the various classes of signs, one of which is the index. Peirce insists that photographs "belong to the second class of signs, those by physical connection." In other words, photographs belong to the index. In the 1970s, American art critic Rosalind Krauss (b. 1941) introduced Peirce's idea about photographs in an article. Since then, this idea has resulted in many arguments among photography critics. Until now, these arguments have fallen into a blind alley. It appears as though the term "index" is useless in describing the twenty-first century notions about photography. However, is Peirce's idea true? In this article, I contend that the index is still relevant in the digital age. According to Peirce, the fact that a photograph "is known to be the effect of the radiations from the object renders it an index." Therefore, the important factor necessary for a photograph to function as an index is that, as Jean-Marie Schaeffer (b. 1953) said, "We know that it is a photograph and know what this fact entails." According to this knowledge, a photograph functions as an index. In the digital age, the function of a photograph as an index is fading. There are two reasons for this. First, in the digital age, the flood of images prevents our efforts to reach the origin of the images. Second, CGI (Computer Generated Image) is indistinguishable from the photographic image, and we know that these CGIs are widely used. Thus, in the digital age, we may not be able to distinguish that it is a photograph.American philosopher Charles Sanders Peirce (1839-1914) categorized the various classes of signs, one of which is the index. Peirce insists that photographs "belong to the second class of signs, those by physical connection." In other words, photographs belong to the index. In the 1970s, American art critic Rosalind Krauss (b. 1941) introduced Peirce's idea about photographs in an article. Since then, this idea has resulted in many arguments among photography critics. Until now, these arguments have fallen into a blind alley. It appears as though the term "index" is useless in describing the twenty-first century notions about photography. However, is Peirce's idea true? In this article, I contend that the index is still relevant in the digital age. According to Peirce, the fact that a photograph "is known to be the effect of the radiations from the object renders it an index." Therefore, the important factor necessary for a photograph to function as an index is that, as Jean-Marie Schaeffer (b. 1953) said, "We know that it is a photograph and know what this fact entails." According to this knowledge, a photograph functions as an index. In the digital age, the function of a photograph as an index is fading. There are two reasons for this. First, in the digital age, the flood of images prevents our efforts to reach the origin of the images. Second, CGI (Computer Generated Image) is indistinguishable from the photographic image, and we know that these CGIs are widely used. Thus, in the digital age, we may not be able to distinguish that it is a photograph.

著者

朝倉 真一 野嶋 政和

出版者

公益社団法人 日本都市計画学会

雑誌

都市計画論文集 (ISSN:09160647)

巻号頁・発行日

vol.33, pp.235-240, 1998-10-25 (Released:2018-04-01)

参考文献数

11

被引用文献数

1

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The purpose of this paper is to examine the spatial structure of the monthly market held on the precincts of Kitano-Tenmangu in Kyoto City by the design survey and the research of the human behavior. As a results of this analysis, it could conclude as follows; (1) This market consists of eight zones, and these zones are more divided to four religious zones and four living-goods zones. (2) It has the religious axis made by the sequence of this stands with the three-dimensional forms, and is connected to the surrounding spaces by the two plaza-type zones. (3) As the spatial structure of his market is made by the combinations of the forms and the arrangements of the stands and the varieties of goods, it is considerable that there are techniques making the space adapted to the environment and the needs of the users without professional designer.

著者

倉持 俊一

出版者

法政大学史学会

雑誌

法政史学 = 法政史学 (ISSN:03868893)

巻号頁・発行日

vol.50, pp.15-33, 1998-03-24

著者

高橋 匡 倉持 俊克 安田 麻衣子 下田 直嗣 平尾 啓

出版者

一般社団法人 情報科学技術協会

雑誌

情報プロフェッショナルシンポジウム予稿集 第12回情報プロフェッショナルシンポジウム

巻号頁・発行日

pp.97-102, 2015 (Released:2015-12-04)

参考文献数

11

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近年、企業を取り巻く環境変化はめまぐるしく、顧客ニーズは多様化している。このような市場環境下、顧客ニーズに対応したイノベーションを継続的に創出するために、社外の技術やアイデアを社内に取り入れるオープンイノベーションを活用し、技術開発を行う企業が増えている。このような背景を受け、2014年度PAT-LIST研究会で顧客ニーズに対応した技術開発を自社で行うか他者と提携して行う(オープンイノベーション)ことが得策かを検証する手法を開発し、消臭技術を対象に実践したので紹介する。

著者

福田 一史 井上 奈智 高倉 暁大 高橋 志行 橋崎 俊 日向 良和 藤倉 恵一 松岡 梨沙

雑誌

じんもんこん2020論文集

巻号頁・発行日

vol.2020, pp.275-282, 2020-12-05

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近年,多くのテーブルトップゲームが創作され消費されるようになった.また図書館でのボードゲームの活用が進むなど文化資源として注目が集まっている.すでにいくつかの民間のデータベースなど実践が存在するが,体系的な目録作成や利用には課題がある.本研究は,1) 既存DBの記述要素分析,2) サンプル資料の分析,3) 産学で組織したワーキンググループでの検討,を通じて概念モデルを策定した.記述テストにより本モデルの有効性が確認できたものの,その妥当性検証や精緻化などの課題が示唆された.

著者

小倉 史愛 木村 丈司 宇田 篤史 戸田 飛鳥 赤澤 由子 山本 和宏 五百蔵 武士 西岡 達也 久米 学 槇本 博雄 平井 みどり

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.42, no.2, pp.78-86, 2016-02-10 (Released:2017-02-15)

参考文献数

34

被引用文献数

2 5

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Polypharmacy, the co-prescribing of nonessential drugs and inappropriate prescriptions, is a worldwide issue and is a factor affecting the increase in adverse drug reactions, drug-drug and drug-disease state interactions, and the growth in medical spending. In this study, we evaluated the current status of polypharmacy in elderly patients at Kobe University Hospital and the efficacy for screening and intervention against potentially inappropriate medications (PIMs) with the screening tool of older persons' potentially inappropriate prescriptions (STOPP) criteria formulated by a pharmacist. Of 301 study patients, 81 (26.9%) patients with PIMs were identified using the STOPP criteria, and these patients had a significantly higher number of prescribed drugs than other patients. Moreover, there was a correlation between the number of prescribed drugs and the percentage of patients identified using the STOPP criteria. The STOPP criteria identified 125 cases to be PIMs, and the prescriptions were changed for 35 (28%) of them. In 125 cases of PIMs, 61 cases had been strongly recommended prescription changes by pharmacists, of which 32 cases (52.5%) had been changed. Several prescription changes were often associated with the administration of nonsteroidal anti-inflammatory drugs. Based on our findings, we suggest that the STOPP criteria are useful for screening PIMs in Japanese patients and are a helpful tool for managing polypharmacy. The benefits of this approach for pharmacists should be multilaterally evaluated by the assessment of patients and medical economic outcomes in the future.

著者

小倉 磐夫

出版者

社団法人 日本写真学会

雑誌

日本写真学会誌 (ISSN:03695662)

巻号頁・発行日

vol.57, no.4, pp.257-261, 1994-08-25 (Released:2011-08-11)