著者

野﨑 秀正 川瀬 隆千 立元 真 後藤 大士 岩切 祥子 坂邉 夕子 岡本 憲和 Hidemasa NOSAKI Takayuki KAWASE Sin TATSUMOTO Hiroshi GOTO Shoko IWAKIRI Yuko SAKABE Norikazu OKAMOTO 宮崎公立大学人文学部 宮崎公立大学人文学部 宮崎大学 都城新生病院 いわきりこころのクリニック 細見クリニック カリタスの園 Miyazaki Municipal University Faculty of Humanities Miyazaki Municipal University Faculty of Humanities Miyazaki University Miyakonojo Shinsei Hospital Iwakiri Mental Care Clinic Hosomi Clinic

雑誌

宮崎公立大学人文学部紀要 = Bulletin of Miyazaki Municipal University Faculty of Humanities (ISSN:13403613)

巻号頁・発行日

vol.28, no.1, pp.105-120, 2021-03-10

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本研究では、子育て支援サービスを提供する公的相談機関に対する母親の援助要請に焦点を当て、母親の育児に対する感情(育児感情)と信念(母性愛信奉)が、援助要請態度を媒介して援助要請意図に影響を及ぼす一連のプロセスを示した仮説モデルを検証することを目的とした。宮崎市内及びその近郊にて就学前の幼児(3 歳以上)の育児に携わる母親1000名に調査協力を依頼した。質問紙が返送され、かつ回答に不備のなかった470 名の回答を分析対象とした。仮説モデルに従い共分散構造分析を行った結果、育児感情及び母性愛信奉から3 つの援助要請態度を媒介して援助要請意図に影響を及ぼすいくつかのプロセスが明らかになった。このうち、利益とコストの態度を媒介したプロセスについては、いずれも子どもにとっての利益とコストを媒介したパスが有意であり、母親自身にとっての利益とコストの態度を媒介したパスはいずれも有意ではなかった。これらの結果より、子育ての悩みに関する母親の公的相談機関に対する援助要請については、母親の精神状態の解決に動機づけられているというよりも、その原因となっている子どもの問題を解決させることに動機づけられていることが明らかになった。こうした結果は、公的相談機関に対する母親の援助要請促進を促すには、援助要請が子どもにもたらすポジティブな影響を強調することや子どもと担当職員間の良好な関係づくりなど、子どもに焦点を当てたアプローチが有効になることを示唆した。

著者

Munehiro YOSHIDA Yuka KIMURA Mamiko ABE Tatsuhiko ANDO Hiroshi TACHI Kenji FUKUNAGA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.47, no.3, pp.248-252, 2001 (Released:2009-04-28)

参考文献数

19

被引用文献数

5 7

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For determination of selenium (Se) in biological materials, an improved method based on high performance liquid chromatographic determination of the fluo-rophore formed by reaction of selenite with 2, 3-diaminonapththalene was developed. The concentration detection limits were 0.5 ng/g in dried materials and 0.03 ng/mL in fluid ma-terials. In quadruplicate assays of 11 biological reference materials using the proposed method, measured Se concentrations were not significantly different from their certified val-ues, Thus, the proposed method is reliable and suitable for the determination of trace levels of Se in foods. Using the proposed method, Se concentrations in various kinds of tea were de-termined to assess the contribution of tea to daily Se intake in the Japanese population. Se concentration in the leaves of general black, green and oolong tea obtained in local retail stores was 33±19 ng/g (n=40). The leaves of a particular Chinese green tea sold under the name “high Se tea” were found to contain 455±184 ng/g (n=14) of Se. While the percent-age of Se extractable by infusion was less than 5% for the general teas, that in the high Se tea was more than 20%. These results indicated that intake of tea does not contribute to daily Se intake in the Japanese population. However, since infusions from high Se tea con-tained over 5 ng/mL of Se, consumption of over 1 L/d of tea derived from such high Se teas may increase the daily Se intake by close to 10%.

著者

Teiichirō Itō Motohiro Nishio Hiroshi Ogawa

出版者

Japan Antibiotics Research Association

雑誌

The Journal of Antibiotics, Series A (ISSN:03681173)

巻号頁・発行日

vol.17, no.5, pp.189-193, 1964 (Released:2020-07-07)

参考文献数

14

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In the course of a research for kanamycin (kanamycin A)1) purification, kanamycin B1) and kanamycin C2) were isolated from the culture broth of Streptomyces kanamyceticus1). Kanamycin B was obtained in pure form by Schmitz, Fardig, O’Herron, Rousche and Hooper8), who isolated deoxystreptamine and 3-amino-3-deoxy-D-glucose after acid hydrolysis of N-acetyl-kanamycin B. Wakazawa, Sugano, Abe, Fukatsu and Kawaji4) reported that partial hydrolysis mixture of kanamycin B still retained some biological activity against B. subtilis, and later they5) isolated a crystalline degradation product which had antibacterial properties.It has been determined that in kanamycins A6,7,8,9) and C10) two aminosugars link to 4- and 6-positions of deoxystreptamine, while in neomycin-group (neomycins B C11,12d) and paromomycin13) the 4,5 hydroxyls of deoxystreptamine are substituted. It should be noted that neomycins are more toxic than kanamycins A and C. As compared with kanamycin A and neomycin S, kanamycin B has more than twice less toxicity than neomycins and has more than five times toxicity than kanamycin A. As reported by Wakazawa et. al.4), kanamycin B can be determined separately from A.In the present paper, our experiments on the structure of kanamycin B are described. Kanamycin B base, which was prepared by the process of Wakazawa et al4) and was recrystallized from ethanol-water, showed [α]24D+ 126° (c, 0.7 in water) and decomposed over the range of 170~190°C. It was soluble in water, but hardly soluble in organic solvent. Its molecular weight was reported to be 1,170 (Rast method, urea as solvent) by Schmitz et al.3) and 385~560 (Barger method, water as solvent) by Wakazawa et al.4) The crystals obtained in our laboratory showed molecular weight of 430~590 by the Rast method (urea as solvent, kanamycin A as standard).N-Acetylkanamycin B3,4) was prepared and, from its hydrolyzates, deoxystreptamine hydrochloride (molecular weight 235) was isolated in the yield of about 30% by weight. The elemental analyses of kanamycin B base and its N-acetyl derivative, together with the above data, suggested the molecular formula C18H37N5O10 for kanamycin B base.

著者

野﨑 秀正 川瀬 隆千 立元 真 後藤 大士 岩切 祥子 坂邉 夕子 岡本 憲和 Hidemasa NOSAKI Takayuki KAWASE Sin TATSUMOTO Hiroshi GOTO Shoko IWAKIRI Yuko SAKABE Norikazu OKAMOTO 宮崎公立大学人文学部 宮崎公立大学人文学部 宮崎大学 都城新生病院 いわきりこころのクリニック 細見クリニック カリタスの園 Miyazaki Municipal University Faculty of Humanities Miyazaki Municipal University Faculty of Humanities Miyazaki University Miyakonojo Shinsei Hospital Iwakiri Mental Care Clinic Hosomi Clinic

雑誌

宮崎公立大学人文学部紀要 = Bulletin of Miyazaki Municipal University Faculty of Humanities (ISSN:13403613)

巻号頁・発行日

vol.28, no.1, pp.105-120, 2021-03-10

---

本研究では、子育て支援サービスを提供する公的相談機関に対する母親の援助要請に焦点を当て、母親の育児に対する感情(育児感情)と信念(母性愛信奉)が、援助要請態度を媒介して援助要請意図に影響を及ぼす一連のプロセスを示した仮説モデルを検証することを目的とした。宮崎市内及びその近郊にて就学前の幼児(3 歳以上)の育児に携わる母親1000名に調査協力を依頼した。質問紙が返送され、かつ回答に不備のなかった470 名の回答を分析対象とした。仮説モデルに従い共分散構造分析を行った結果、育児感情及び母性愛信奉から3 つの援助要請態度を媒介して援助要請意図に影響を及ぼすいくつかのプロセスが明らかになった。このうち、利益とコストの態度を媒介したプロセスについては、いずれも子どもにとっての利益とコストを媒介したパスが有意であり、母親自身にとっての利益とコストの態度を媒介したパスはいずれも有意ではなかった。これらの結果より、子育ての悩みに関する母親の公的相談機関に対する援助要請については、母親の精神状態の解決に動機づけられているというよりも、その原因となっている子どもの問題を解決させることに動機づけられていることが明らかになった。こうした結果は、公的相談機関に対する母親の援助要請促進を促すには、援助要請が子どもにもたらすポジティブな影響を強調することや子どもと担当職員間の良好な関係づくりなど、子どもに焦点を当てたアプローチが有効になることを示唆した。

著者

Yoshitaka HARADA Yuki OHMURO-MATSUYAMA Mika TSUNA Hiroshi UEDA

出版者

The Japan Society for Analytical Chemistry

雑誌

Analytical Sciences (ISSN:09106340)

巻号頁・発行日

vol.37, no.3, pp.455-459, 2021-03-10 (Released:2021-03-10)

参考文献数

13

被引用文献数

4

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Immunochromatography assay is an easy and rapid on-site detection method. However, conventional sandwich immunochromatographies using two antibodies can only detect target molecules above a threshold size. Small molecules below 1000 in molecular weight are usually detected using competitive immunoassay. However, competitive immunoassay is not suitable for visual detection of low concentration samples. Based on the principles of open sandwich immunoassay, which detects small molecules via interchain interaction of separated variable region fragments (VH and VL) from a single antibody, we developed non-competitive open sandwich immunochromatography. Bone Gla protein (BGP)-C7, a peptide containing the seven C-terminal amino acids of human osteocalcin, was selected as the target. By using VL fragments fixed on a nitrocellulose membrane, and colored cellulose bead-labeled VH fragments, we specifically detected 10 ng/mL of BGP-C7. This is the first report of open sandwich immunochromatography, which is an easy and rapid method for on-site, signal-on detection of small molecules.

著者

中辻 萬治 荒居 和子 杉澤 秀博 長田 久雄 柴田 博 Manji NAKATSUJI Kasuko ARAI Hidehiro SUGISAWA Hisao OSADA Hiroshi SHIBATA

雑誌

老年学雑誌 = Journal of gerontological research (ISSN:21859728)

巻号頁・発行日

vol.4, pp.93-112, 2014-03-20

著者

和泉 浩 IZUMI Hiroshi

出版者

秋田大学教育文化学部

雑誌

秋田大学教育文化学部研究紀要. 人文科学・社会科学自然科学 (ISSN:1348527X)

巻号頁・発行日

vol.70, pp.9-20, 2015-03-01

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Despite the power of social capital and community resilience after disasters has been recognized, the postdisasterrecoveries and disaster mitigations after the Great East Japan Earthquake and Tsunami have still continuedto focus resources on physical infrastructures, based almost exclusively on data and knowledge of natural sciences.Against this backdrop or below the surface many sociological and ethnological studies on the Great East JapanEarthquake and Tsunami shed light on effective functioning of local communities and their social capital, or socialnetworks for the post-disaster recoveries and disaster mitigations; local community enhances individual andcommunity resilience. Some literatures point out the importance of local cultures and their traditional rituals orbuild environments and spaces of the rituals, and argue for the need for the “archive” of their memories because ofthe literally devastating effects of the Great East Japan Earthquake and Tsunami on local communities and theirmembers, but they mainly select the cultural masterpieces of local community – macro-memory or Memory ofcommunity, like museums and galleries select and collect the masterpieces of humankind. This paper theoreticallyexplores the relationships among social, collective memories, traditional rituals of local communities and socialcapital, and unveils the important functions of collective micro-memories of everyday life and social networks,which are too familiar to speak about, intentionally memorize – unspoken and pre-conscious, but one of the keyfactors for social capital and community resilience.

著者

Naoki Shibata Norio Umemoto Akihito Tanaka Kensuke Takagi Makoto Iwama Yusuke Uemura Yosuke Inoue Yosuke Negishi Taiki Ohashi Miho Tanaka Ruka Yoshida Kiyokazu Shimizu Hiroshi Tashiro Naoki Yoshioka Itsuro Morishima Toshiyuki Noda Masato Watarai Hiroshi Asano Toshikazu Tanaka Yosuke Tatami Yasunobu Takada Hideki Ishii Toyoaki Murohara on behalf of N-Registry Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-20-0545, (Released:2021-03-20)

参考文献数

39

被引用文献数

3

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Background:Data regarding the clinical features, outcomes and prognostic factors in patients presenting with acute total/subtotal occlusion of the unprotected left main coronary artery (LMCA) remain limited.Methods and Results:From a multi-center registry, 134 patients due to acute total/subtotal occlusion of the unprotected LMCA were reviewed. Emergency room (ER) status classification was defined according to the presence of cardiogenic shock and cardiopulmonary arrest (CPA) in the ER (class 1=no cardiogenic shock; class 2= cardiogenic shock but not CPA; and class 3=CPA). In-hospital mortality and cerebral performance category (CPC) as the endpoints were evaluated. One-half (67/134) of the enrolled patients presented with total occlusion of the unprotected LMCA. Regarding ER status classification, class 1, 2, and 3 were observed in 30.6%, 45.5%, and 23.9% of the patients, respectively. In-hospital mortality occurred in 73 (54.5%) patients; of the remaining patients, 52 (85.3%) could be discharged with a CPC 1 or 2. ER status classification (odds ratio 4.4 [95% confidence interval: 2.33–10.67]; P<0.001) and total occlusion of the unprotected LMCA (odds ratio 8.29 [95% confidence interval 2.93–23.46]; P<0.001) were strong predictors of in-hospital mortality.Conclusions:Acute total/subtotal occlusion involving the unprotected LMCA appeared to be associated with high in-hospital mortality. ER status classification and initial flow in the unprotected LMCA were significant predictive factors of in-hospital mortality.

著者

Mitsukazu Mitsugi Yoko Hisamoto Hiroshi Suzuki

出版者

Carcinological Society of Japan

雑誌

Crustacean Research (ISSN:02873478)

巻号頁・発行日

vol.46, pp.83-94, 2017 (Released:2017-03-10)

参考文献数

34

被引用文献数

3 6

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An invasive freshwater shrimp of the genus Neocaridina Kubo, 1938 (Decapoda: Caridea: Atyidae) was collected from the Tomoe River of the Boso Peninsula, Tateyama City, Chiba Prefecture, eastern Japan. We compared the morphological characteristics and mitochondrial DNA sequence variation of the specimens with those of other Neocaridina species. In particular, we assessed the mitochondrial DNA region encoding the NADH dehydrogenase subunit 2 [ND2] gene and the region encoding the NADH dehydrogenase subunit 5 [ND5] gene. Our specimens are most likely to be Neocaridina davidi (Bouvier, 1904), a species native to mainland China. This species may have entered Japan through intentional disposal or accidental escape from aquaria.

著者

Yuiko Nagamine Takeo Fujiwara Yukako Tani Hiroshi Murayama Takahiro Tabuchi Katsunori Kondo Ichiro Kawachi

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.30, no.11, pp.497-502, 2020-11-05 (Released:2020-11-05)

参考文献数

36

被引用文献数

8

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Background: Socioeconomic mobility affects health throughout the life course. However, it is not known whether there are gender differences in the association between life-course subjective socioeconomic status (SSS) mobility and mortality at older ages.Methods: Participants were 16,690 community-dwelling adults aged 65–100 years in the Japan Gerontological Evaluation Study (JAGES). Baseline information including demographic characteristics, depression, and lifestyle factors were collected in 2010. Participants’ vital status was confirmed in 2013 via linkage to death records. We categorized life-course socioeconomic mobility into the following categories: ‘persistently high’, ‘downward mobility’, ‘upward mobility’, and ‘persistently low’. Cox proportional hazard modeling was used to estimate hazard ratios (HR) for all-cause mortality.Results: Mortality HRs for the ‘downward’ group were 1.37 (95% confidence interval [CI], 1.08–1.74) among men and 1.27 (95% CI, 0.94–1.71) among women in comparison with the ‘persistently high’ group. Compared to the ‘persistently low’ group, the HRs for the ‘upward’ group were 0.54 (95% CI, 0.35–0.83) among women and 0.91 (95% CI, 0.73–1.24) among men. Associations were not changed after adjusting for objective socioeconomic status but were attenuated by depression.Conclusions: ‘Downward’ mobility was associated with mortality among men, but not among women. Depression appeared to mediate the association. A protective effect of upward mobility was observed among women but not among men.

著者

関 智弥 池田 宏 SEKI Tomoya IKEDA Hiroshi

出版者

Terrestrial Environment Research Center, the University of Tsukuba

雑誌

筑波大学陸域環境研究センター報告 = Bulletin of the Terrestrial Environment Research Center,the University of Tsukuba (ISSN:13463381)

巻号頁・発行日

vol.4, pp.75-88, 2003-10

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Lake Kasumigaura is a coastal lake, the second largest lake in Japan. There is the lacustrine lowland with a width of 0.5 - 1.0km, around Lake Kasumigaura. The lacustrine lowland consists of "Terrace I", "Terrace II" and "developing Lowland". It has been known that the lacustrine lowland formed at present, however the mechanisms and processes of formation have not been well understood. Thus, in this study, geomorphic characters and mechanism of developing lowland are revealed by distributions of reed community and grain size analysis and analysis of wave energy.Developing lowland is low and flat topography, and its relative height is 0 - 0.5m from mean water level. And its structure materials are mainly fine grains especially "very fine sand" and "silt". In addition distributions of the developing lowland and reed community have close correlation. And these distributions are determined mainly by wave energy.These results lead to the conclusion that developing lowland was formed with deposition of sands by the wave and capture of fine grains by reeds.

著者

Hiroshi NISHIYAMA Alexander MARTIN Keiichi HATANO Sumiaki KISHIMOTO Nobuhiro SASAKI Kyle G. WEBBER Ken-ichi KAKIMOTO

出版者

The Ceramic Society of Japan

雑誌

Journal of the Ceramic Society of Japan (ISSN:18820743)

巻号頁・発行日

vol.129, no.3, pp.127-134, 2021-03-01 (Released:2021-03-01)

参考文献数

38

被引用文献数

6

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While lead-free (Li,Na,K)NbO3 piezoceramics have a high Curie temperature (TC > 400 °C) and an excellent piezoelectric constant (d33 > 200 pC/N), the process window regarding the sintering temperature and dwelling time is narrow. Inappropriate sintering conditions can induce the volatilization of A-site alkali ions, leading to a deterioration in dielectric and piezoelectric properties. However, the effect of alkali volatilization on the ferroelastic properties is still uncertain. In this study, (Li,Na,K)NbO3 piezoceramics were deliberately exposed to the sintering temperature for varying times to compare the susceptibility of the effect of alkali volatilization on the ferroelastic properties and compared to changes in the ferroelectric and ferroelastic and dielectric properties.

著者

鈴木 和博 Suzuki Kazuhiro 中村 俊夫 Nakamura Toshio 加藤 丈典 Kato Takenori Takenori 池田 晃子 Ikeda Akiko 後藤 晶子 Goto Akiko 小田 寛貴 Oda Hirotaka 南 雅代 Minami Masayo 上久保 寛 Kamikubo Hiroshi 梶塚 泉 Kajizuka Izumi 足立 香織 Adachi Kaori 壺井 基裕 Tsuboi Motohiro 常磐 哲也 Tokiwa Tetsuya 太田 友子 Oota Tomoko 西田 真砂美 Nishida Masami 江坂 直子 Esaka Naoko 田中 敦子 Tanaka Atsuko 森 忍 Mori Shinobu ダンクリー ダニエル Dunkley Daniel J. クシャク モニカ Kusiak Monika A. 鈴木 里子 Suzuki Satoko 丹生 越子 Niu Etsuko 中崎 峰子 Nakazaki Mineko 仙田 量子 Senda Ryoko 金川 和世 Kanagawa Kazuyo 熊沢 裕代 Kumazawa Hiroyo

出版者

名古屋大学年代測定資料研究センター

雑誌

名古屋大学加速器質量分析計業績報告書

巻号頁・発行日

vol.19, pp.26-38, 2008-03

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Umi is located along the Kamimura River within the Kamiyahagi area of southeastern Ena City, Gifu Prefecture. The name 'Umi' means sea or large lake; however, there are no lakes in the mountainous Kamiyahagi area. The Tokai Gou (torrential rain) flood of September 11-12, 2000 destroyed embankments along the river, and exposed sedimentary layers that are typical of a lacustrine depositional setting. This confirms the existence of a paleo-lake from which the name Umi originated. The ^<14>C ages, ranging from 280±37 to 345±25 BP, appear to be contemporaneous with Tensho Earthquake that occurred in central Japan on January 18, 1586.

著者

島田 延枝 寺沢 敏夫 内藤 統也 松井 洋 星野 真弘 向井 利典 山本 達人 斎藤 義文 國分 征 町田 忍 SHIMADA Nobue TERASAWA Toshio NAITO Tsuguya MATSUI Hiroshi HOSHINO Masahiro MUKAI Toshifumi YAMAMOTO Tatsundo SAITO Yoshifumi KOKUBUN Susumu MACHIDA Shinobu

出版者

宇宙科学研究所

雑誌

宇宙科学研究所報告 (ISSN:02852853)

巻号頁・発行日

vol.98, pp.1-23, 1997-11

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1994年2月20日01UTに発生した太陽フレアは, その伝播過程で強い惑星間空間衝撃波を生じた。太陽風中をモニターしていたGEOTAIL衛星は, 翌日2月21日09UTにこの衝撃波と遭遇し, 粒子分布や磁場等のプラズマ状態を詳細に観測することができた。その結果, このイベントに幾つかの特筆すべき現象がみられることが明らかになった。高周波まで及ぶ比較的強い磁場波動が観測された他, イオンのみならず, 電子に於いても衝撃波フェルミ加速の結果といえる分布とエネルギースペクトルが得られた。1AUに於いて電子の衝撃波統計的フェルミ加速のはっきりした証拠が得られることは, 大変希である。本稿では, 電子の衝撃波フェルミ加速現象の報告を中心に, それに関連する観測結果を述べていきたい。

著者

西川 宏 Hiroshi Nishikawa

出版者

同志社大學經濟學會

雑誌

経済学論叢 (ISSN:03873021)

巻号頁・発行日

vol.19, no.1, pp.1-37, 1970-03

著者

山口 宏 Hiroshi Yamaguchi

雑誌

日本福祉大学社会福祉論集 = Journal of social welfare, Nihon Fukushi University

巻号頁・発行日

no.113, pp.1-18, 2005-08-31

著者

Koichi Izumikawa Hiroshi Kakeya Fumikazu Sakai Kazutoshi Shibuya Takashi Sugita Takahiro Takazono Tohru Takata Masato Tashiro Katsuji Teruya Shigeki Nakamura Hiromitsu Noguchi Masataro Hiruma Koichi Makimura Taiga Miyazaki Yoshitsugu Miyazaki Yuka Yamagishi Koichiro Yoshida Akira Watanabe

出版者

The Japanese Society for Medical Mycology

雑誌

Medical Mycology Journal (ISSN:21856486)

巻号頁・発行日

vol.61, no.4, pp.61-89, 2020 (Released:2020-11-30)

参考文献数

39

被引用文献数

7

著者

Hiroto MORITA Mutsuki ICHISHIMA Ipputa TADA Hirotsugu SHIROMA Makoto MIYAGI Teppei NAKAMURA Hiroshi TANAKA Shinya IKEMATSU

出版者

BMFH Press

雑誌

Bioscience of Microbiota, Food and Health (ISSN:21863342)

巻号頁・発行日

vol.40, no.1, pp.75-79, 2021 (Released:2021-01-08)

参考文献数

24

被引用文献数

2

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Ogimi is one of Japan’s longevity villages and is located in Okinawa Prefecture. In this study, we focused on the elderly women living in the village, classified them into two groups based on whether or not they lived in Ogimi during the first 3 years of their lives, and compared the gut microbiota between the two groups. There were no differences in alpha and beta diversity; however, we found that the elderly women who lived in Ogimi during the first 3 years of their lives had a higher rate of Akkermansia muciniphila colonization in their guts.

著者

Tetsuya Tsujikawa Akira Makino Hiroshi Oikawa Shota Ishida Tetsuya Mori Yasushi Kiyono Hirohiko Kimura Hidehiko Okazawa

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2020-0129, (Released:2021-02-09)

参考文献数

22

被引用文献数

2

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Purpose: To compare apparent diffusion coefficients (ADCs) of bone marrow on diffusion-weighted imaging (DWI) between two fat-suppression techniques, and to evaluate the association between bone-marrow ADCs and the proton density fat fraction (PDFF).Methods: Seventy-seven patients underwent whole-body DWI with short-inversion time inversion-recovery (STIR) (DWISTIR) and/or STIR + selective water-excitation (spectral-spatial RF [SSRF]) (DWISTIR+SSRF). ADCs of lumbar vertebrae (L3 and L4) were compared between DWISTIR and DWISTIR+SSRF, and correlated with the PDFF.Results: Lumbar ADCs obtained by DWISTIR and DWISTIR+SSRF were significantly correlated (L3: r = 0.90, P < 0.0001, L4: r = 0.90, P < 0.0001). Lumbar ADCs (× 10-6 mm2/s) obtained by DWISTIR were significantly lower than those by DWISTIR+SSRF (L3: 479 ± 137 and 490 ± 148, P < 0.05, L4: 456 ± 114 and 471 ± 118, P < 0.005). Residual fat signals were more clearly observed on DWISTIR than on DWISTIR+SSRF. The ADCs of L3 obtained by DWISTIR and DWISTIR+SSRF exhibited significant positive correlations with the PDFF (r = 0.51, P < 0.0001, and r = 0.45, P < 0.0001, respectively), and the ADCs of L4 obtained by DWISTIR and DWISTIR+SSRF exhibited significantly positive correlations with the PDFF (r = 0.40, P < 0.0005, and r = 0.40, P < 0.0005, respectively).Conclusion: Irrespective of different fat-suppression methods, lumbar ADCs were positively correlated with the PDFF, being inconsistent with previous studies. Lumbar ADCs obtained by DWISTIR were significantly lower than those obtained by DWISTIR+SSRF, probably due to residual fat signals on DWISTIR. However, this difference (< 4%) did not explain the positive correlation between lumbar ADC and PDFF.

著者

森泉 陽子 Moriizumi Yoko 飯塚 信夫 Iizuka Nobuo 小川 浩 Ogawa Hiroshi 谷沢 弘毅 Yazawa Hirotake 外木 好美 Tonogi Konomi 松村 敏 Matsumura Satoshi

出版者

神奈川大学経済貿易研究所

雑誌

経済貿易研究 : 研究所年報 (ISSN:03865193)

巻号頁・発行日

vol.41, pp.15-27, 2015-03-25

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座談会 森泉陽子先生御退職記念