著者

本田 知之

出版者

日本神経感染症学会

雑誌

NEUROINFECTION (ISSN:13482718)

巻号頁・発行日

vol.27, no.1, pp.45, 2022 (Released:2022-05-12)

参考文献数

45

---

【要旨】ボルナウイルスは、近年、致死性脳炎を引き起こす病原体として、ヨーロッパを中心に着目されているが、その認知度は依然低いままである。致死性疾患につながるボルナウイルス感染症の脅威に備えるためには、このウイルスの基本情報を知ることが重要である。本稿では、ボルナウイルスの基本情報とヒトにおけるボルナウイルス感染症の病態を概説する。ボルナウイルスは宿主に持続感染する点が一つの特徴であり、特にその持続感染病態メカニズムについては私たちの研究成果をいくつか紹介したい。さらに、臨床家がボルナウイルス感染症を鑑別診断として考慮すべき症例を具体的に提案することで、この感染症の認知度の向上と対策に貢献できれば幸いである。

著者

竹井 絵理 真柄 仁 辻村 恭憲 井上 誠

出版者

日本顎口腔機能学会

雑誌

日本顎口腔機能学会雑誌 (ISSN:13409085)

巻号頁・発行日

vol.26, no.1, pp.26-27, 2019 (Released:2021-01-30)

被引用文献数

1

著者

福島 卓 松浦 晃宏 苅田 哲也 森 大志

出版者

The Society of Physical Therapy Science

雑誌

理学療法科学 (ISSN:13411667)

巻号頁・発行日

vol.37, no.4, pp.387-391, 2022 (Released:2022-08-20)

参考文献数

22

---

〔目的〕重心移動練習課題中の前庭機能を抑制することを目的とした経頭蓋直流電気刺激(tDCS)が重心移動学習を促進させるかを検討した.〔対象と方法〕健常成人10名を対象とし,重心移動練習課題中に右側乳様突起部へ3分間陰極通電するtDCS条件と課題開始後30秒間通電するsham刺激条件を比較した.練習課題前後に,前後・左右方向の足圧中心(CoP)変位と下肢荷重量を計測した.同時に下腿の表面筋電図を記録した.〔結果〕tDCS条件では,練習実施後にCoPが右側へ有意に変位し,右下肢荷重量が増大した.〔結語〕前庭tDCSは立位重心移動誘導を促進させるツールとなり得る可能性がある.

著者

福嶋 路

出版者

研究・イノベーション学会

雑誌

研究 技術 計画 (ISSN:09147020)

巻号頁・発行日

vol.35, no.4, pp.472-475, 2021-05-27 (Released:2021-05-22)

著者

井上 茂

出版者

日本法哲学会

雑誌

法哲学年報 (ISSN:03872890)

巻号頁・発行日

vol.1957, pp.241-362, 1958-03-30 (Released:2009-02-12)

参考文献数

165

著者

CHAUHAN Anubhuti

出版者

公益社団法人 日本語教育学会

雑誌

日本語教育 (ISSN:03894037)

巻号頁・発行日

vol.170, pp.47-61, 2018 (Released:2020-08-26)

参考文献数

20

---

本研究では,ヒンディー語を母語とする日本語学習者に見られる対のある自動詞・他動詞 (以下,自他動詞) の誤用傾向・使用実態を学習期間別,自動詞・他動詞別に調査した。その結果,下位群では,述語選択の誤用が最も多く,中位群では,格助詞選択の誤用が比較的多かった。そして,上位群ではヴォイスに関する誤用が占める割合と述語・格助詞の選択に関わる誤用の割合にはあまり差が見られなくなった。つまり,先行研究で指摘されている通り,自他動詞の習得段階が「語彙を選択する→格助詞を選択する→文法的で意味が通じる文を作れる」のように展開していくことが窺えた。しかし,自動詞・他動詞別に考察すると,自動詞では,3群ともに述語選択の誤用が最も多く,他動詞の習得段階と異なり,語彙習得が助詞習得に必ずしも先立つわけではないことが示唆された。対のある自動詞の過剰使用による誤用の原因として,ヒンディー語が自動詞表現を好む言語であることが考えられた。

著者

Mohammad Al Sorkhy Zina Fahl Jenna Ritchie

出版者

The Japanese Society of Strategies for Cancer Research and Therapy

雑誌

Annals of Cancer Research and Therapy (ISSN:13446835)

巻号頁・発行日

vol.26, no.1, pp.19-25, 2018-01-16 (Released:2018-03-27)

参考文献数

46

被引用文献数

9 9

---

Breast cancer (BC) is a commonly diagnosed cancer amongst women and the second leading cause of cancer deaths in the world. BC has created huge challenges to healthcare providers regarding the identification of main risk factors and how they contribute to the development of the disease. Several studies suggest that biological risk factors such as duration of breast feeding, age at menarche, menopausal status and the use of contraceptive pills have contributed to the increase of BC diagnoses. Moreover, psychological factors such as depression, stress and negative lifestyles are gaining more attention as a major contributor to this type of cancer. The role of psychological stress regarding BC has been widely demonstrated in the literature across several fields including but not exclusive to epidemiology, physiology, and molecular biology which all show a clear relationship between intracellular stress signaling and protumorigenic pathways within breast cells. Cortisol is primary stress hormone of the human body and a growing body of research both clinically and molecularly are revealing a positive correlation of high cortisol levels and the progression of BC. This review attempts to establish and highlight how cortisol levels impact breast cancer development and progression.

著者

辻 惟雄

出版者

美学会

雑誌

美学 (ISSN:05200962)

巻号頁・発行日

vol.29, no.3, pp.49, 1978-12-30 (Released:2017-05-22)

---

As has long been discussed from various points of view, a close relationship exists between art and play. The materials for such discussions, however, have been limited for the most part to the works of western arts. In this paper I would like to point out that such materials have also abundantly existed throughout the history of Japanese painting. In proof of the existence of play moment in Japanese art, at first we shall focus our attention on paintings in the late Heian Period, especially Oko-e, the extempore caricature drawings-executed in a light and easy style-which were popular among 11th century aristocrats. These Oko-e served as the model for later comic descriptions found in master handscroll works in the 12th century such as "Shigisan-engi Emaki", "Chojugiga", "Jigoku-zoshi" and so on, because of their fluencies and vividnesses in describing style. Secondly is considered in this paper the existence of the curious art critic known as "Enan-ho" ("Picture-Accusing Priest") who played the clown at Court, works of pornographic caricature called Osokuzu-no-e, and the trompe-l' 〓il of waterfall which was painted on the wall of a noble's hermitage for the purpose of astonishing guests. Finally we might point out that the spirit of playfulness also existed vividly in paintings of the Edo Period.

著者

佐藤 将

出版者

学校法人 東洋大学現代社会総合研究所

雑誌

現代社会研究 (ISSN:1348740X)

巻号頁・発行日

vol.2022, no.20, pp.45-54, 2022 (Released:2023-07-07)

著者

Ya-Nan Ma Xuemei Jiang Wei Tang Peipei Song

出版者

International Research and Cooperation Association for Bio & Socio-Sciences Advancement

雑誌

BioScience Trends (ISSN:18817815)

巻号頁・発行日

vol.17, no.5, pp.335-355, 2023-10-31 (Released:2023-11-18)

参考文献数

165

被引用文献数

3

---

Studies have found that intermittent fasting (IF) can prevent diabetes, cancer, heart disease, and neuropathy, while in humans it has helped to alleviate metabolic syndrome, asthma, rheumatoid arthritis, Alzheimer's disease, and many other disorders. IF involves a series of coordinated metabolic and hormonal changes to maintain the organism's metabolic balance and cellular homeostasis. More importantly, IF can activate hepatic autophagy, which is important for maintaining cellular homeostasis and energy balance, quality control, cell and tissue remodeling, and defense against extracellular damage and pathogens. IF affects hepatic autophagy through multiple interacting pathways and molecular mechanisms, including adenosine monophosphate (AMP)-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR), silent mating-type information regulatory 2 homolog-1 (SIRT1), peroxisomal proliferator-activated receptor alpha (PPARα) and farnesoid X receptor (FXR), as well as signaling pathways and molecular mechanisms such as glucagon and fibroblast growth factor 21 (FGF21). These pathways can stimulate the pro-inflammatory cytokines interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α), play a cytoprotective role, downregulate the expression of aging-related molecules, and prevent the development of steatosis-associated liver tumors. By influencing the metabolism of energy and oxygen radicals as well as cellular stress response systems, IF protects hepatocytes from genetic and environmental factors. By activating hepatic autophagy, IF has a potential role in treating a variety of liver diseases, including non-alcoholic fatty liver disease, drug-induced liver injury, viral hepatitis, hepatic fibrosis, and hepatocellular carcinoma. A better understanding of the effects of IF on liver autophagy may lead to new approaches for the prevention and treatment of liver disease.

著者

山下 祐介

出版者

東北社会学会

雑誌

社会学年報 (ISSN:02873133)

巻号頁・発行日

vol.43, pp.65-74, 2014-07-25 (Released:2015-08-24)

参考文献数

20

被引用文献数

3

---

本稿では,1995年に生じた阪神・淡路大震災と,2011年東日本大震災について,ボランティア・支援・復興の各側面における検証を試みる.95年阪神・淡路大震災はボランティア革命とも言われ,その後の日本の市民活動活発化の起因となった.今回の東日本大震災は,この市民活動領域の形成が市民社会を日本にもたらしたのかを知る機会であったと言える.本稿では,とくに福島第一原発事故をめぐる復興政策および支援活動の中でその検証を行う.今後,日本的な市民社会が形成されるための条件として,地方自治の確立,科学の適切な政策利用,これらをふまえた市民活動の政治的作動が必要になると議論した.

著者

川原田 康

出版者

一般社団法人 日本農村医学会

雑誌

日本農村医学会雑誌 (ISSN:04682513)

巻号頁・発行日

vol.70, no.5, pp.515-522, 2022 (Released:2022-02-20)

参考文献数

9

---

我々は分類不能癌と微小浸潤型腺癌,上皮内腺癌の異なる病理像の三重多発肺癌を経験したので報告する。症例は71歳男性。S状結腸癌術前の胸部CTで両肺の結節およびすりガラス結節(ground glass nodule:GGN)を指摘されていた。増大がなく経過観察されていたが,7年目のCTで左肺下葉の空洞性結節が壁肥厚を来たし悪性の可能性が否定できず。2か月後のCTで急速に増大あり,また左肺門リンパ節も急速に増大し,cT2aN1M0,stage ⅡBと判断した。手術を施行したが,左肺門リンパ節が気管分岐部および左主肺動脈まで浸潤しており,左肺全摘術を行なったが完全切除はできなかった。病理結果から左肺門部腫瘤は分類不能癌,左肺下葉の空洞性病変は微小浸潤型腺癌,左肺上葉のGGNは上皮内癌の結果であり,同時性三重多発肺癌と判断した。本症例では手術が予後の延長には寄与しなかったが,文献的には同時性多発肺癌に対して根治切除を行なうことで良好な予後が得られた症例も報告されている。画像所見から安易に多発肺転移と判断せずに,同時性多発肺癌である可能性も考慮した治療選択が必要であると考える。

著者

本田 正美

出版者

日本社会情報学会

雑誌

日本社会情報学会全国大会研究発表論文集 日本社会情報学会 第26回全国大会

巻号頁・発行日

pp.461-466, 2011 (Released:2012-03-20)

---

Since the late 1990s, in order to adapt to the information society, e-government policy initiatives have been deployed around the world. However, the concrete contents of the initiatives are different in each country. The reason is thought to be mentioned that the e-government policy initiatives have been affected by the existing institutions and policies in each country. It seems that, among countries with different systems, new policies that are thought to have same purposes would differ in its contents. In this study, therefore, it analyzes the relationship between existing institutions and e-government policy initiatives. Specifically, it considers the relationship between freedom of information system and e-government policy initiatives in the United Kingdom. Based on the consideration, it reveals the characteristics of e-government policy in the UK.

著者

清水 栄司

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.111, no.11, pp.2311-2316, 2022-11-10 (Released:2023-11-10)

参考文献数

10

---

エビデンスに基づいた精神療法である認知行動療法は,これまでうつ病や不安症のような精神疾患に用いられてきた.より簡便な低強度の認知行動療法では,ワークブックやデジタル・セラピューティックスとしてのアプリの形で患者に提供することが可能であり,禁煙外来だけでなく,プライマリケアで通常みられる肥満症,糖尿病,肝疾患,慢性疼痛などの内科診療でも大いに活用できる可能性があるので,本稿で紹介する.

著者

阪本 清美 坂下 誠司 山下 久仁子 岡田 明

出版者

ヒューマンインタフェース学会

雑誌

ヒューマンインタフェース学会論文誌 (ISSN:13447262)

巻号頁・発行日

vol.19, no.1, pp.119-128, 2017-02-25 (Released:2018-12-10)

参考文献数

11

被引用文献数

1

---

We carried out experiments to investigate the relationship between display resolution and physiological and psychological state during the viewing of 4K and 2K content on a 65-inch 4K TV as a comparison between age groups. During viewing tests of 4K scenic content by participants in their 20s and 50s, psychological evaluation scores and NIRS, an index of nervous system activity, were significantly higher during 4K scenic content viewing than for 2K viewing. However, the effect of the display resolution for content comprising video images of fine objects such as food, jewels, watches, glass and fur, was limited compared to that for scenic content between age groups. Our results suggest that content viewing at 4K tends to cause psychological elation and a surge in brain activity, although the effects varied somewhat according to content, and these effects of display resolution on physiological and psychological state were found regardless of age groups.

著者

丹羽 絹子

出版者

政治経済学・経済史学会

雑誌

歴史と経済 (ISSN:13479660)

巻号頁・発行日

vol.61, no.4, pp.34-51, 2019-07-30 (Released:2021-07-30)

参考文献数

41

---

This paper explores how tea became Britain’s national drink beginning in the mid‒nineteenth century, with a focus on the tea‒tax reduction of 1853. Tea had been spreading in Britain since early in the eighteenth century, but there was a critical turning point in tea consumption around the mid‒nineteenth century as seen in changes in historical per capita consumption. Many reasons are apparent for the increase in tea consumption in the latter half of the nineteenth century, including tax reform, expansion of colonial plantations and developments in advertising and sales methods. Among these, the tax reform of 1853 was the driving force in affecting the timing of the change in consumption patterns. Previous studies have not elaborated on this subject, but the background of the tax reform and its relation to tea consumption merit detailed explanation.By examining the report of the Select Committee of the House of Commons in 1847 concerning the tea‒tax reduction and parliamentary debates, this paper reveals three factors affecting the changes in consumption pattern : economic interests in the China market, ideological developments regarding working‒class consumers, and political considerations pertaining to the public as consumers.Firstly, in the late 1840’s, British manufacturers became involved in the tea market by way of the barter trade involving British products and tea in China. This affected tea prices in the British market while at the same time accelerating political action on behalf of tea‒tax reduction by those with interests in the Chinese market.Secondly, from the mid‒nineteenth century, working‒class tea consumption was supported by the middle‒classes, which shared ideological views on the importance of free trade, temperance and improvement of working‒class conditions. In addition, Chartists who tried to take the initiative in political reform for the working class also promoted working‒class tea consumption in the course of their activities. Thus, these ideologies and movements formed a public opinion favorable to the mass consumption of tea and contributed to the realization of a reduction in the tax on tea.Finally, reflecting the demands of the middle and working classes, it became increasingly important for politicians of the time to develop policies with mass consumers in mind. Implementation of the tea‒tax reduction was thus a symbol of this change in awareness among politicians.From the above it can be concluded that the steady increase in the consumption of tea from the mid‒nineteenth century on, and the eventual establishment of tea as a national beverage, were due to the fact that a broad swath of society including middle class, working class, and politicians agreed, for both economic and ideological reason, on the desirability of expanding the consumption of tea by the masses.

著者

長田 紀之(おさだ のりゆき)

出版者

独立行政法人 日本貿易振興機構アジア経済研究所

雑誌

アジア動向年報 (ISSN:09151109)

巻号頁・発行日

vol.2023, pp.423-446, 2023 (Released:2023-08-25)

著者

谷貝 祐介 古山 宣洋 三嶋 博之

出版者

日本認知科学会

雑誌

認知科学 (ISSN:13417924)

巻号頁・発行日

vol.26, no.2, pp.197-218, 2019-06-01 (Released:2019-12-01)

参考文献数

42

被引用文献数

2

---

In drum-set playing,drummers need to maintain accurate and powerful performance.What kind of postural control makes it possible to achieve this? The present study investigated the differences in postural control between expert (N=3) and novice (N = 4) drum-set players.Participants in this study performed an 8-beat rhythm pattern using an electric drum set consisted of hi-hat cymbals,a snare drum,and a bass drum.Tap-pressure data of each instrument and center-of-pressure (CoP) data of the participant were recorded and analyzed. As indices of performance accuracy and intensity,mean and standard deviation (SD) of inter-tap interval (ITI) and mean and coefficient of variation peak tap force applied to each instrument were calculated from the tap-pressure data.A principal component analysis was performed to compute the area of CoP and the circular SD of the principal component angle.The area of CoP and the circular SD were used to evaluate the magnitude of movement and the variance in movement direction, respectively. We found the followings: As for the experts,the SD of ITI and circular SD were small and consistent across the individuals,while the individual differences was relatively large in the peak tap force and area of CoP.The SD of ITI and circular SD of the novices were comparable to those of the experts.The individual differences in the drum-set playing skills seemed to be dependent on musical background of the individuals.

著者

米良 克美

出版者

学校法人 グロービス経営大学院大学

雑誌

グロービス経営大学院紀要 (ISSN:27584046)

巻号頁・発行日

vol.2, pp.107-110, 2023-11-30 (Released:2023-12-05)

---

働く社会人において,日々勉強し自身の知識やスキルを更新し続けることは,自身の価値を高めることにつながる.しかし,働く社会人が日々どの程度勉強しているのか,さらには,日々の勉強時間と主観的幸福度の関係については明らかにされていない.そこで本研究では,日本の働く社会人における勉強時間の実態を調べるとともに,勉強時間と主観的幸福度の関係を明らかにすることを目的とした.日本の働く社会人において,日々勉強している人の割合は36%であり,その勉強内容や勉強方法はさまざまであった.また,職位が高いほど,年収が高いほど,1日あたりの勉強時間が長かった.さらに,日々勉強していない人と比べて,勉強している人の方が高い主観的幸福度,キャリア満足度,仕事能力に対する自信を示すことが明らかとなった.

著者

平野 祐也 竹永 正輝 西川 尚志 丸山 寛人 浅野 日登美 椎名 星歩 千葉 麻由 武田 雄太 渡邊 真輝 橋 本直

出版者

特定非営利活動法人 日本バーチャルリアリティ学会

雑誌

日本バーチャルリアリティ学会論文誌 (ISSN:1344011X)

巻号頁・発行日

vol.26, no.2, pp.155-158, 2021-06-30 (Released:2021-06-30)

参考文献数

5

---

The parasitism of plants on the human body often appears in fiction, however until now it was limited to the expression in media such as novels, illustrations, and movies. Therefore, we created "Brain Tree" which enables appreciators to experience the sensation of plant parasitizing on their head. In this work, we used a head massager to present the sensation of plant roots invade the head. Furthermore, various tactile expressions are incorporated to enrich the experience such as the feeling that water penetrates into the head by watering, the feeling that the parasitic plant absorbs the nutrients in the appreciator’s head, and the feeling of the plant swaying in the wind. In this paper, we report the system design, implementation, experience design, and appreciators’ feedbacks in exhibitions.