著者
任 玉洁 林 雅子
出版者
日本パーソナリティ心理学会
雑誌
パーソナリティ研究 (ISSN:13488406)
巻号頁・発行日
vol.29, no.1, pp.23-26, 2020-05-07 (Released:2020-05-07)
参考文献数
18

The purpose of this study was to examine the effect of parental bonding instrument (PBI) on over-adaptation in adolescence from the viewpoint of gender difference. The participants were 299 university students (male=125; female=174). The results showed that the level of mother’s loving on the PBI positively predicted boys’ and girls’ external aspect (EA) of over-adaptation, but negatively predicted girls’ internal aspect (IA) of over-adaptation. The level of mother’s overprotectiveness on the PBI was found to positively predict both EA and IA in adolescence. The level of father’s overprotectiveness on the PBI was positively associated with IA in boys; however, it was not significantly correlated with IA in girls.
著者
春田 純一
出版者
公益社団法人 日本薬学会
雑誌
MEDCHEM NEWS (ISSN:24328618)
巻号頁・発行日
vol.25, no.3, pp.128-131, 2015-08-01 (Released:2018-11-01)
参考文献数
11
被引用文献数
2

JTオリジナル新薬、抗HIV薬elvitegravirと抗腫瘍薬trametinibの開発ストーリーをエピソードを交えながら紹介する。創薬には化学、生物、医学、物理(分析機器の発展)等の最先端のサイエンスが必須であることは論を待たない。創薬には時間がかかり、数々の困難に出会い、それらを解決して次へと進め、そしてほんの一握りのプロジェクトが成功する。そんな長くて遠い創薬の道を乗り切るには理論だけではどうにもならない時がある。その時、理論以外の「何か」が必要である。それを浮き彫りにしたい。
著者
本中 真
出版者
社団法人 日本造園学会
雑誌
造園雑誌 (ISSN:03877248)
巻号頁・発行日
vol.55, no.3, pp.223-231, 1991-02-28 (Released:2011-07-19)
参考文献数
40

前報では, 橘俊綱が白河上皇との会話の中で「地形」「眺望」を指標として選定した4庭園をとりあげ, 4者の相互の形態的な比較検討を試みた。そして彼の選抜に合格した庭園と選に漏れた庭園との差を明らかにし, 同時に彼の挙げた2つの選考指標の意味についても明らかにした。本報告は, さらに考察を進めて2人の間に交わされた会話の政治的背景を探り, 選考基準のいま一つの性格について明らかにしようとするものである。
著者
若井 郁次郎
出版者
水資源・環境学会
雑誌
水資源・環境研究 (ISSN:09138277)
巻号頁・発行日
vol.27, no.2, pp.51-56, 2014 (Released:2014-12-27)
参考文献数
5
被引用文献数
2

4 4 4 4 OA 仏無線通信史

著者
中野 幸紀
出版者
日仏経営学会
雑誌
日仏経営学会誌 (ISSN:09151206)
巻号頁・発行日
vol.32, pp.1-17, 2015 (Released:2019-09-12)
参考文献数
14
著者
Maria Teresa B Abola Jonathan Golledge Tetsuro Miyata Seung-Woon Rha Bryan P Yan Timothy C Dy Marie Simonette V Ganzon Pankaj Kumar Handa Salim Harris Jiang Zhisheng Ramakrishna Pinjala Peter Ashley Robless Hiroyoshi Yokoi Elaine B Alajar April Ann Bermudez-delos Santos Elmer Jasper B Llanes Gay Marjorie Obrado-Nabablit Noemi S Pestaño Felix Eduardo Punzalan Bernadette Tumanan-Mendoza
出版者
Japan Atherosclerosis Society
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
pp.53660, (Released:2020-07-04)

Background: Peripheral artery disease (PAD) is the most underdiagnosed, underestimated and undertreated of the atherosclerotic vascular diseases despite its poor prognosis. There may be racial or contextual differences in the Asia-Pacific region as to epidemiology, availability of diagnostic and therapeutic modalities, and even patient treatment response. The Asian Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD) thus coordinated the development of an Asia-Pacific Consensus Statement (APCS) on the Management of PAD. Objectives: The APSAVD aimed to accomplish the following: 1) determine the applicability of the 2016 AHA/ACC guidelines on the Management of Patients with Lower Extremity Peripheral Artery Disease to the Asia-Pacific region; 2) review Asia-Pacific literature; and 3) increase the awareness of PAD. Methodology: A Steering Committee was organized to oversee development of the APCS, appoint a Technical Working Group (TWG) and Consensus Panel (CP). The TWG appraised the relevance of the 2016 AHA/ACC PAD Guideline and proposed recommendations which were reviewed by the CP using a modified Delphi technique. Results: A total of 91 recommendations were generated covering history and physical examination, diagnosis, and treatment of PAD—3 new recommendations, 31 adaptations and 57 adopted statements. This Asia-Pacific Consensus Statement on the Management of PAD constitutes the first for the Asia-Pacific Region. It is intended for use by health practitioners involved in preventing, diagnosing and treating patients with PAD and ultimately the patients and their families themselves.
著者
宮川 栄一
出版者
神戸大学
雑誌
国民経済雑誌 (ISSN:03873129)
巻号頁・発行日
vol.200, no.6, pp.37-55, 2009-12
著者
渡邊 浩
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.108, no.5, pp.962-963, 2019-05-10 (Released:2020-05-10)
参考文献数
7
著者
大石 和徳 佐藤 弘 多屋 馨子
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.140, no.7, pp.901-904, 2020-07-01 (Released:2020-07-01)
参考文献数
4

Although rubella is usually a mild, febrile illness, and up to 50% of rubella infections are asymptomatic, congenital rubella syndrome (CRS) can occur in the developing fetus of a pregnant woman infected with rubella virus (RV) in early pregnancy. After a rubella outbreak from early 2012 to late 2013 in Japan, another outbreak re-emerged from mid-2018 in the Tokyo metropolitan area and other large cities. In 2018, and up to epidemiological week (EW) 25 in 2019, more than 4000 rubella cases had been reported. Three CRS cases were also reported up to EW 24. Seroepidemiological surveys among Japanese residents indicated that the susceptible pocket to RV in male adults aged 30-50 years, as determined in 2013, remained unchanged in 2018. To reduce the number of male adults sensitive to RV, in early 2019, Japan's Ministry of Health, Labour and Welfare decided to implement routine immunization of male adults aged 40-57 years between 2019 and 2021. These male adults have been determined to have low anti-RV antibodies, and were therefore designated as the target population for this routine immunization (as category A). Although one-third of male patients with rubella reported in 2018 were in their 20 s and 30 s, these younger generations were not included in the target population for routine immunization against rubella, because they had already received a routine vaccination. Rubella vaccination is also required for male adults aged 20-40 years to diminish the susceptible pocket.
著者
前田 知己
出版者
一般社団法人 日本小児神経学会
雑誌
脳と発達 (ISSN:00290831)
巻号頁・発行日
vol.52, no.3, pp.141-146, 2020 (Released:2020-06-30)
参考文献数
36

脳性麻痺の早期介入・支援に向けて, 早期診断の重要性が増している. 乳児期早期に行える脳性麻痺の予測に有用な神経学的評価の文献をレビューすると, general movements (GMs) 評価が最も多く報告されている. 本稿では, 月齢3〜4までの新生児期・乳児期早期に実施できる発達評価法について紹介し, GMs評価法について詳述する. 脳性麻痺の予測には予定日から3〜4か月時のfidgety運動の欠如が最も重要な所見である. GMsに関する知識は小児神経医にとって重要であるが, 本邦ではGMsの評価者が少なく評価能力の研修, 維持が困難なことが普及への課題である.
著者
桂 敏夫
出版者
The Japan Society for Oriental Medicine
雑誌
日本東洋医学雑誌 (ISSN:02874857)
巻号頁・発行日
vol.46, no.2, pp.293-299, 1995-09-20 (Released:2010-03-12)
参考文献数
10
被引用文献数
1

腹痛に対しては普通, 芍薬甘草湯 (以下芍甘湯とする) が用いられるが, 甘草湯もこれに劣らず有用である。外来で日頃遭遇する腹痛の中では, 急性の感冒やこれに伴う胃腸炎による一過性のものが多いが, 1年間子供を主とする130例に対してこの両者を内服と口に含むだけの2通りの方法で止痛までの時間を測定した。この2薬方と2方法の4通りのいずれにもほとんど差がなく, 大部分のものは数分から10分以内で腹痛が消失した。
著者
三星 知 山田 仁志 山崎 修治 小林 真理子 上野 和行 長井 一彦
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.140, no.7, pp.943-947, 2020-07-01 (Released:2020-07-01)
参考文献数
19

Concomitant therapy with acetaminophen (APAP) and low-dose aspirin is often used in clinical settings; however, it is unclear whether this combination is involved in the progression of chronic kidney disease (CKD). We hypothesized that concomitant therapy with APAP and low-dose aspirin may cause CKD progression. We carried out a retrospective 6-year cohort study that included all patients who received low-dose aspirin from January 2011 to December 2016 at Kaetsu Hospital. Primary outcome was defined as CKD progression at the end of the study compared with baseline. Among the 441 patients treated during the study period, we identified 89 cases of CKD progression. Multivariate regression analysis showed that exposure to APAP>50 g [odds ratio (OR), 2.68, 95% confidence interval (CI), 1.08-6.70], age increase by 1 year (OR, 1.05, 95% CI, 1.02-1.08), and diabetes mellitus (OR, 2.40, 95% CI, 1.41-4.08) had positive associations with CKD progression. Our findings suggested that concomitant therapy with APAP and low-dose aspirin increased the risk of CKD progression. Therefore, we recommend more thorough monitoring of serum creatinine when patients are on such concomitant therapy. Moreover, it is important to advise users of low-dose aspirin to avoid unnecessary use of APAP, in order to reduce the risk of CKD progression.
著者
Aya Ueda Shinji Toki Chisato Kitayama Manabu Akazawa
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.43, no.7, pp.1135-1140, 2020-07-01 (Released:2020-07-01)
参考文献数
19

Inappropriately reduced doses (IRDs) of direct oral anticoagulants (DOACs) are common in clinical practice. We performed a retrospective review using electronic medical records of St. Marianna University School of Medicine Hospital (a 1200-bed teaching hospital in Japan) to address the prevalence of IRDs and patient-related factors that result in IRDs. We also surveyed DOAC-treated patients who were hospitalized due to a stroke during the 5-year study period to analyze the association between stroke events and IRDs. We found that one in five patients who were newly prescribed a DOAC was treated with IRDs. Patients treated with edoxaban received the most IRDs (64%, 7/11), followed by those treated with dabigatran (50%, 1/2), apixaban (32%, 19/61), and rivaroxaban (27%, 12/44). Our analysis showed that the renal function (measured as serum creatinine and creatinine clearance values) and age are possible factors influencing dose reduction. The HAS-BLED score and antiplatelet use were not associated with IRD prescription. An analysis of the 5-year hospital records revealed 20 stroke cases despite ongoing treatments with DOACs, and IRDs were noted in three of these cases. In all three cases, the patients had been on an IRD of rivaroxaban. To prevent IRDs of DOACs, we suggest that a clinical protocol be incorporated into formularies to support the prescription process.
著者
経塚 淳子
出版者
The Japanese Society of Plant Morphology
雑誌
PLANT MORPHOLOGY (ISSN:09189726)
巻号頁・発行日
vol.19and20, no.1, pp.29-37, 2008 (Released:2010-06-28)
参考文献数
48

植物は胚発生以降も葉の腋に新しい茎頂メリステム(腋生メリステム)をつくり,そこから分枝を増やすことにより生涯にわたり形態形成を続ける.イネ科植物の花序はいくつかの異なるタイプの分枝で構成されており,それぞれのタイプの分枝の組み合わせが種に固有の花序の形をつくる.したがって,腋生メリステムの形成,その分化運命の決定,分枝の成長パターンにより花序の基本構造が決定される.本稿ではイネやトウモロコシなどイネ科植物を中心に,分枝パターンの決定に関わる遺伝的制御に関する知見を紹介する.